Protein Alignment CG12869 and cest-10

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_501133.3
• Gene: cest-10 / 177493
• WormBaseID: WBGene00016595
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 569
• Identity: 135/569 - (23%)
• Similarity: 217/569 - (38%)
• Gaps: 122/569 - (21%)

  Fly    11 LRLLP-----ILIHLSPYISA--QQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINEL 68
            :.|||     .|...|.::.:  .:|.:....||.|          |..:.|..||:|:.|:.:|
 Worm     1 MHLLPGIQILFLFSFSCFVDSVIVETSLGKLNGDQI----------GNFHLFKKIPFAKPPLGKL 55

  Fly    69 RFAPAKPSSSFNRTLQATTMQPLCPQLANTIYDESSDGSMPRSVS--TDEDCLYLNIWTPESGMR 131
            ||...:|:.::|....|....|.|          .|:.|..::|.  .|||||:|||:|.|:.::
 Worm    56 RFQKPQPAETWNGVRNAKDYGPAC----------MSNSSTTKTVQKWVDEDCLHLNIFTSETCLK 110

  Fly   132 YGKLPIVVIVTGEEFAYDWPRNRINGLDL----AGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGN 192
            .....:|:.:.|....|| .....|...|    |.:.||.|....|..|:....: |.....|.|
 Worm   111 SKNCAVVIYLHGGNLHYD-SAVMFNDTFLLHTYASQEIVFVIPAVRLGIFSHFVV-EDQSIAPNN 173

  Fly   193 YGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVA----TLEDSSQVKQLVLMSPGP 253
            ..|.|:..|:.:.:.:...||||....|||||..||...::::    ...|.|..:|.:.||...
 Worm   174 LALFDMLQAMEFAKSDIHNFGGNNKRTTLLGHSYGGTVASMLSFSTKVNTDLSLFQQYISMSSPT 238

  Fly   254 IMRALGQNHQKWIVETGQVLVQKLGC-----QFEEAQRRQ--LMGCLRRKSREDLLRAYESVYNH 311
            ....|     :..||......:...|     :|....:::  :..||::||..:|||...|:...
 Worm   239 NFDTL-----ELQVERTYRFAEHANCLPKNSKFMRKNQKEVYMRDCLKKKSASELLRIQRSLEEA 298

  Fly   312 G----NGSSQLGVILPEGLPLE--QRLRNKTLPPVLLGITSNEGAFLQDYWLDVAREGQVALHKY 370
            |    .||...|.|..|.|..:  ....|.|   .|.|.|..| :.:.|::.::.:......::.
 Worm   299 GYPVYGGSVMRGPIFQEVLERDFMDSPNNIT---SLTGCTKYE-SLVYDHYRNMGKALGFENYEE 359

  Fly   371 INHTLLPNVMRA-LESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILE 434
            :|.....:.... :|....:::||:..|:.|             ..:.::|.:::....|
 Worm   360 VNEKYRSDSKEGKIEFDNVKNATQIMLIQIR-------------TRVNKILKKNIPAYHY----- 406

  Fly   435 LLNGTTSYAYVFDHSHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIR 499
                  .|||   ..|             |:|:.||..::|...|.|      ...|.:|....|
 Worm   407 ------EYAY---PKH-------------ANHTDDLFFIMGVHPFIQ------DENEIKLGNFYR 443

  Fly   500 GAFANFIKNGNPTPGRIYDG------------WLPYNKENPFVYSLGEQ 536
            ..|.||||.||  ||...||            |.....|.|.:.:..||
 Worm   444 SMFLNFIKTGN--PGNGCDGANLNGSTYFEVNWNETTGERPVMKNNFEQ 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	130/546 (24%)
cest-10	NP_501133.3	Abhydrolase	23..503	CDD:389770	130/547 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900