Protein Alignment CG12869 and cest-6

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_501070.1
• Gene: cest-6 / 177459
• WormBaseID: WBGene00020688
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 532
• Identity: 128/532 - (24%)
• Similarity: 218/532 - (40%)
• Gaps: 113/532 - (21%)

  Fly    16 ILIHLSPYISAQQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFN 80
            :||..|.|.|.:...|....|.:.|.::      |:...|..||:|:.||.:|||.....:..:.
 Worm    11 LLIVYSAYKSCEAGVITTSLGSINGNQI------GSYQTFKKIPFAKPPIGKLRFQKPMAAEKWE 69

  Fly    81 RTLQATTMQPLCPQLANTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKLPIVVIVTGEE 145
            ..|.||...|.|  ::|     ||....|:. ..|||||::||:|.::.:......:|..|.|.|
 Worm    70 GILNATEYGPAC--MSN-----SSTSKSPQK-WIDEDCLHINIFTTDTCLSSKNCSVVFYVHGGE 126

  Fly   146 FAYDWPRNRINGLD------LAGEGIVVVSVQYRNNIYGWLSLGEQHRNV-PGNYGLSDVQMALR 203
            ..||   :.:...|      .:...:::|...:|..::....:.:|  || |.|..|.|:.:||.
 Worm   127 LVYD---SAVMFEDKYLFDTFSSRDVILVIPAFRLGLFSHFVVEDQ--NVAPNNLALYDILLALE 186

  Fly   204 WIRRNADAFGGNPDHITLLGHGSGGAPLALVA-TLE---DSSQVKQLVLMSPGPIMRALGQNHQK 264
            :::.....|||:.|.:|..||..||..::::| :.|   |.|..::::.||...:..:|     :
 Worm   187 FVKSEIHNFGGSSDRVTAFGHSYGGHVVSVMAFSTEINTDLSYFQRVICMSSVNVWDSL-----E 246

  Fly   265 WIVETGQVLVQKLGC-----------QFEEAQRRQLMGCLRRKSREDLLRAYESVYNHGNGSSQL 318
            :.:|.....:|...|           .||  |...:|.||:.....:|||...|:.:.|: ....
 Worm   247 FEIEKTMRFIQYANCSVPQDLKSRMTSFE--QDSYMMECLQDIDSMELLRIQRSLEDEGH-PIYS 308

  Fly   319 GVILPEGLPLEQRL-------RNKTLPPVLLGITSNEGAFLQDYWLDVAREGQVALHKYINHTLL 376
            |::|.|  ||.|.:       :.|.: |.|.|.|..|        ||       ..|.|.|
 Worm   309 GLVLRE--PLIQNVLVQDFYEKPKNI-PTLTGCTYKE--------LD-------KFHAYHN---- 351

  Fly   377 PNVMRALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRI---LELLNG 438
                 .:|::|.|:..:...   :|.:.:..|...|    .:...|:...|..:::   .:|..|
 Worm   352 -----IVETLGYENYKECDD---KYRDDRKYGRFDL----NKHADETFGILAQTKLKVDKQLDKG 404

  Fly   439 TTSYAYVFDH-SHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRGAF 502
            ..:|.|.:.: .|             .||:.||..::|...|::      ...|..|.:..:..|
 Worm   405 IPTYFYEYSYPKH-------------PSHTDDLSYIMGVHAFEK------DENEIHLAKSYQEMF 450

  Fly   503 ANFIKNGNPTPG 514
            .||:|.|.|..|
 Worm   451 MNFVKFGEPGGG 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	123/521 (24%)
cest-6	NP_501070.1	alpha/beta hydrolases	25..500	CDD:473884	123/518 (24%)