Protein Alignment CG12869 and cest-27

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_871861.2
• Gene: cest-27 / 171610
• WormBaseID: WBGene00018958
• Length: 561
• Species: Caenorhabditis elegans
• Alignment Length: 535
• Identity: 126/535 - (23%)
• Similarity: 208/535 - (38%)
• Gaps: 105/535 - (19%)

  Fly    46 DGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIYDESSDGSMPR 110
            ||:  .|..|||||||:.||..|||........:...|......|..||         :|..:.:
 Worm    44 DGS--VVEGFLGIPYAEPPIGALRFKKPVAHRKWTEPLDCVRFGPRSPQ---------NDELLGQ 97

  Fly   111 SVST----DEDCLYLNIWTP--ESGMRYGKLPIVVIVTGEEFAYDWPRN---RINGLDLAGEGIV 166
            .|:|    :|.||.||::||  ||.......|::|.:.|..||.....|   .....:|..:.:|
 Worm    98 FVNTVGKSEEHCLSLNVFTPKWESNEWPDGFPVMVFIHGGGFAVHSSSNYGCASIARNLCTKDVV 162

  Fly   167 VVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPL 231
            ||::.||..:.|:.:.|::  ...||.||.|...||.|::.|..:|.|:||::|:.|..:|||.:
 Worm   163 VVTINYRLGVLGFFTTGDE--VCRGNLGLWDQTAALEWVQENIQSFRGDPDNVTIFGQSAGGASV 225

  Fly   232 ALVATLEDSSQVKQLVLMSPGPIMRALGQNHQKWIVETGQVLVQKLGCQFEEAQRRQLMGCLRRK 296
                         .|:.:||          |.:.:......:.....|.|......|.....|..
 Worm   226 -------------DLLCLSP----------HSRGLFNRAIPMAGNGECDFAMRTSEQQAQLSREF 267

  Fly   297 SR-----------EDLLRAYESV--------------YNHGNGSSQL------GVILPEGLPLEQ 330
            :|           ||||:..:..              :.|....|..      |...|:  ||.|
 Worm   268 ARYLGWEGDDNDSEDLLQFIDQQPLYKIEMGINPKRGFKHSQAGSLYFVPNFDGDFFPK--PLNQ 330

  Fly   331 RLRNKTLPPVLLGITSNEGAFLQDYWLDVAREGQVALHKYINHTLLPNVMRALESVGEESSTQLA 395
            ..:......::.|.|..||.|.  ..|....:....:.|::.     .:.:..: .||.:...|.
 Worm   331 LRKEAPKMQIMTGTTKYEGLFF--IALGALSKNPEGIKKFMG-----RIFKECD-YGERADDVLQ 387

  Fly   396 AIRWRYFNG----KGEGVSHLLAGMQRLLSESLYELPYS--RILELLNGTTS--YAYVFDHSHSM 452
            .:...||.|    ..|...|.:.   :.:.:  |.:.|.  |:..::.....  |.|.||:.:|.
 Worm   388 MVYDFYFKGVHPKDHEKNMHQIV---KFIGD--YSINYGTYRLANIMTDLQHDVYFYQFDYHNSA 447

  Fly   453 DMRGRRNL--FGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNPTPGR 515
            .....|.|  |.|::|.:::..:||..:   |::.|.:..::::...:...|.||.|.|||....
 Worm   448 GFGVFRWLLPFLGSTHCTEMRYVLGKGI---ISKFRPNDNDKKMLHVMTTYFTNFAKYGNPNGEN 509

  Fly   516 IYDG-WLPYNKENPF 529
            ...| |..::..:||
 Worm   510 QETGEWQKHDSAHPF 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	126/535 (24%)
cest-27	NP_871861.2	COesterase	29..541	CDD:278561	126/535 (24%)
		Aes	<114..>283	CDD:223730	46/193 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910