Protein Alignment CG12869 and Ces2c

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_598270.2
• Gene: Ces2c / 171118
• RGDID: 621510
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 644
• Identity: 165/644 - (25%)
• Similarity: 267/644 - (41%)
• Gaps: 136/644 - (21%)

  Fly     2 W-NALRIQQILRLLPILIHL----SPYISA-QQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPY 60
            | ||:    :..||.||||:    ||..|: :.||....:|.|..::    .|:..|:.|||||:
  Rat     9 WLNAV----LFGLLLILIHVWGQDSPESSSIRTTHTGQVRGKLDHVR----DTKAGVHTFLGIPF 65

  Fly    61 AQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIYDESSDGSMP---RSVSTDEDCLYLN 122
            |:||:..|||||.:....::.....|:...:|.|..:.: ||.....|.   .|:...|||||||
  Rat    66 AKAPVGPLRFAPPEDPEPWSGVRDGTSHPAMCLQNIDML-DEVGLTDMKMILSSIPMSEDCLYLN 129

  Fly   123 IWTPESGMRYGKLPIVVIVTGEEFAYDWPRNRINGLDLAGEGIVVVSVQYRNNIYGWLSLGEQHR 187
            |:||........||::|.:.|..............|....|.:|||::|||..:.|:.|.|::|.
  Rat   130 IYTPAHAHEGSNLPVMVCIHGGALVIGMASMCDGSLLAVNEDLVVVAIQYRLGVLGFFSTGDEHA 194

  Fly   188 NVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSP- 251
            .  ||:|..|...||||:::|...|||||:.:|:.|..:||..:        ||.|     :||
  Rat   195 R--GNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGVSAGGTSV--------SSHV-----ISPM 244

  Fly   252 ------GPIMR---ALGQNHQKWIVETGQVLVQKL-GCQFEEAQRRQLMGCLRRKSREDLL---R 303
                  |.||.   ||..:......||....|.|| ||:..:::  .|:.|||.||..::|   :
  Rat   245 SQGLFHGAIMESGVALLPDLISETSETVSTTVAKLSGCEATDSE--TLVRCLRAKSGAEILVINK 307

  Fly   304 AYESVYNHGNGSSQLGVILPEGLPL--EQRLRNKTLPPV--LLGITSNEGAFLQDYWLDVAREGQ 364
            .::.:         ..|:..|.||.  ::.|.::...||  ::|:.::|..
  Rat   308 VFKMI---------PAVVDGEFLPRHPKELLASEDFHPVPSIIGVNTDEYC-------------- 349

  Fly   365 VALHKYINHTLLPNVMRALESVGEESSTQLAAI-----------------RWRYFNGKGEGVSHL 412
                     ..:|.||...:.:.|.|...|.|:                 ....:.|..:....|
  Rat   350 ---------CTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPPECGDLLMEEYMGNTDDPQTL 405

  Fly   413 LAGMQRLLSESLYELPYSRILELLNG-TTSYAYVFDHSHSMDMRGRRNLFGGASHSSDLPLLLGP 476
            ......::.:.|:.:|..::...... ...|.|.|.|:.|. .:..|.....|.|:.::|.:.|
  Rat   406 QIQYAEMMGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSY-FKNVRPPHVKADHADEVPFVFG- 468

  Fly   477 SLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNPTPGRIYDGWLPYNKENPFVYSLGEQAKTPQ 541
            |.|..| :..|:.||:.|.|::...:|||.::|||            |.|.           .|.
  Rat   469 SFFWGI-KVDFTEEEKLLSRRMMKYWANFARHGNP------------NSEG-----------LPY 509

  Fly   542 TGSVDEAEVDKLLRGETGAPGLDRSLSRSNRHDTYRAAPSNSYTASNQLDSGYSNHLQM 600
            ...:|..|  :.|:.:| .|.:||:|.........:..|..    ..:|:....||.::
  Rat   510 WPVLDHDE--QYLQLDT-QPAVDRALKARRLQFWTKTLPQK----IQELNGAQKNHAEL 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	140/552 (25%)
Ces2c	NP_598270.2	COesterase	32..540	CDD:395084	150/590 (25%)