Protein Alignment CG12869 and Ces1e

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_598421.1
• Gene: Ces1e / 13897
• MGIID: 95432
• Length: 562
• Species: Mus musculus
• Alignment Length: 596
• Identity: 162/596 - (27%)
• Similarity: 260/596 - (43%)
• Gaps: 120/596 - (20%)

  Fly    16 ILIHLSPYISAQQTH------IKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAK 74
            ||:.|:.: :|...|      :...||.::|..:..:|....|..|||:|:|:.|:..|||||.:
Mouse     7 ILVSLAAF-TAGAGHPSSPPMVDTVQGKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQ 70

  Fly    75 PSSSFNRTLQATTMQPLC------PQLANTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGMRYG 133
            |:..::....||:..|:|      .|:.|.:.....: .:|...|  ||||||||:||....:..
Mouse    71 PAEPWSSVKNATSYPPMCFQDPVTGQIVNDLLTNRKE-KIPLQFS--EDCLYLNIYTPADLTKSD 132

  Fly   134 KLPIVV------IVTGEEFAYDWPRNRINGLDLA-GEGIVVVSVQYRNNIYGWLSLGEQHRNVPG 191
            :||::|      :|.|....||       ||.|: .|.:|||.:|||..|:|:.|.|::|..  |
Mouse   133 RLPVMVWIHGGGLVLGGASTYD-------GLVLSTHENVVVVVIQYRLGIWGFFSTGDEHSR--G 188

  Fly   192 NYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMR 256
            |:|..|...||.|::.|...|||:|..:|:.|..:||            ..|..|||   .|:.:
Mouse   189 NWGHLDQVAALHWVQDNIAKFGGDPGSVTIFGESAGG------------ESVSVLVL---SPLAK 238

  Fly   257 ALGQNHQKWIVETGQVLVQKL----------------GCQFEEAQRRQLMGCLRRKSREDLLRAY 305
            .|   .|:.|.|:|..|...|                ||  :......::.|||:|:.|:||...
Mouse   239 NL---FQRAISESGVALTAGLVKKNTRPLAEKIAVISGC--KNTTSAAMVHCLRQKTEEELLGTT 298

  Fly   306 ------------ESVYNHGNGSSQL-GVILPEGLPLEQRL--RNKTLPPVLLGITSNEGAFLQDY 355
                        :|..:|....:.| ||:||: :| |:.|  :|....|.::||...|..::...
Mouse   299 LKLNLFKLDLHGDSRQSHPFVPTVLDGVLLPK-MP-EEILAEKNFNTVPYIVGINKQEFGWILPT 361

  Fly   356 WL-----DVAREGQVALHKYINHTLLPNVMRALESVGEESSTQLAAIRWRYFNGK---GEGVSHL 412
            .:     ||..:...|:......:.|.|:.....:|..|          :|...|   |.....|
Mouse   362 MMNYPPSDVKLDQMTAMSLLKKSSFLLNLPEDAIAVAIE----------KYLRDKDYTGRNKDQL 416

  Fly   413 LAGMQRLLSESLYELPYSRILELLN---GTTSYAYVFDHSHSMDMRGRRNLFGGASHSSDLPLLL 474
            |    .|:.:.::.:| |.|:...:   |..:|.|.|.:|.|.....:.:...| .|..::..:.
Mouse   417 L----ELIGDVVFGVP-SVIVSRGHRDAGAPTYMYEFQYSPSFSSEMKPDTVVG-DHGDEIYSVF 475

  Fly   475 GPSLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNPTPGRIYDGWLPYNKENPFVYSLGEQAKT 539
            |    ..|.|...|.||..|.:.:...:|||.:||||. |:....|..|:::..:: .:|  |.|
Mouse   476 G----APILRGGTSEEEINLSKMMMKFWANFARNGNPN-GQGLPHWPEYDQKEGYL-QIG--ATT 532

  Fly   540 PQTGSVDEAEV 550
            .|...:.|.||
Mouse   533 QQAQKLKEKEV 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	154/574 (27%)
Ces1e	NP_598421.1	COesterase	25..546	CDD:278561	157/577 (27%)
		Aes	44..>242	CDD:223730	75/227 (33%)
		Prevents secretion from ER. /evidence=ECO:0000255	559..562

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910