Protein Alignment CG12869 and LOC1280747

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: XP_061513099.1
• Gene: LOC1280747 / 1280747
• VectorBaseID: AGAMI1_007562
• Length: 1118
• Species: Anopheles gambiae
• Alignment Length: 887
• Identity: 202/887 - (22%)
• Similarity: 313/887 - (35%)
• Gaps: 268/887 - (30%)

  Fly    52 VYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIYDESSD-GSMPRS---- 111
            |..|..:|||..||..|||.|.|....:..|..|.|...:|||....|.:.::. .|||:.
Mosquito    97 VEVFKAVPYATPPIGSLRFEPPKKLPPWKGTKLADTFGSVCPQSFPDISNRTAALLSMPKGRYQH 161

  Fly   112 --------VSTDEDCLYLNIWTPESGMRYGKLP--IVVIVTGEEFAYDW-PRNRINGLDLAGEG- 164
                    .:..||||.|||:.|.||.|..:.|  |...:.||  |||| ..|..:|..||..|
Mosquito   162 LKRLQPLLANQSEDCLTLNIYVPGSGSRGLEAPYSIFFYIHGE--AYDWGSGNPYDGSVLASYGH 224

  Fly   165 IVVVSVQYRNNIYGWL----SLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHG 225
            ::||:|.:|..|.|:|    ||..   ...||.||.|:.:||:|:|.|..:|||:|..||::||.
Mosquito   225 VIVVTVNFRLGILGFLKTRASLSP---GSGGNLGLMDIILALQWVRDNIASFGGDPKRITIVGHD 286

  Fly   226 SGGAPLALVATLEDSSQ--VKQLVLMSPGPIMRALGQNHQKW--IVETGQV---LVQKLGCQFEE 283
            :|.| ||.:|.:..:.:  |::.:|:|        |.....|  |.:...|   :.|::.|....
Mosquito   287 TGAA-LANLALISKAGKGLVQRAILLS--------GSALSPWALIPDPDAVRLEVSQQMACHLVP 342

  Fly   284 AQRRQ------LMGCLRRKSREDLLRAYESVYNHGNGSSQLGV------ILPEG---LPLEQRLR 333
            .:..:      :..|||.|..|.|                :||      .:|..   ||||.
Mosquito   343 GRNGRKPTTDDITECLRDKPIEAL----------------MGVRLTSVRFMPSWGPFLPLED--- 388

  Fly   334 NKTLPP---------------VLLGITSNE-----GAFLQDYWLDVAREGQVALHKYINHTLLPN 378
              ::.|               ::||:|:.|     .|....|.|:..:..:: |..||.:....:
Mosquito   389 --SMDPEFAMEHSGEGFITSELMLGMTTTESYSDFSASDIQYGLEEDQRNRL-LRTYIRNAFTFH 450

  Fly   379 VMRALESVGEESSTQLAAIRWRYFNGKGEGVSH---LLAGMQRLLSESLYELPYSRI--LELLNG 438
            :.....:|..|.:.      |      .:.:.|   :.......||:.....|..::  |....|
Mosquito   451 LNEIFSAVRNEYTD------W------DKPIQHPINIRDSTMEALSDGHTVAPIIKVAYLHARRG 503

  Fly   439 TTSYAYVFDHSHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQ--QIARRRFSGEEEQLCRKIRGA 501
            ..:|.:.|.: .|.:....:.|  |:....|||.:.|..|.|  .:..:.:|.::..:...:...
Mosquito   504 AKTYMFHFGY-QSKESEYPQRL--GSVRGEDLPYIFGLPLVQGGPVFPQNYSRQDMGVNEAVLNF 565

  Fly   502 FANFIKNGNPTPGRIYDGWLPYNKENPFVYSLGEQAKT---PQTGSVDEAEVDKLLRGETGAPGL 563
            ..||.|.|:|.                   ..|.|...   |..|:..|....:|:..||.....
Mosquito   566 VTNFCKTGDPN-------------------EAGHQQAAPLHPDYGTAKERTRFRLITWETYETTT 611

  Fly   564 DRSLSRSNRHDTYRAAPSNSYTASNQLDSGYSNHLQMVYGFWQVLMP-LEREEDLRGGGALGQRV 627
            .:.||.|.:               .::.|.|..|..   ..|..|:| |.|..|
Mosquito   612 QQYLSISTK---------------PKMRSHYRGHKM---ALWLNLIPQLHRPGD----------- 647

  Fly   628 RLLEASADAARYRQGFYAMLGLVCLLLACLCLCVYLLKRDPN----AMRRRSASSASDCYSLXHK 688
              .|.|.....:|:                        |:|:    ::|..|.|.....|.
Mosquito   648 --PEVSMRHHHFRE------------------------REPHYYAGSVRAESFSRPRSLYQ---- 682

  Fly   689 WFRWTTIFGGRKDEVPSTSGIAN-VESWRKGGRATKREQDGS-------GAVESGGGDGN----- 740
                              :|:.| .:..|:....|:...|.:       ..|..|||.|:
Mosquito   683 ------------------NGVINDAQESRQESFGTECTPDPTMGEVLQENGVGGGGGPGDTLTNV 729

  Fly   741 LEGERREQVLNKQRTRRPRQLQPYDFKITHPIG-GAGVG-----------AGF-----------G 782
            |..|..|::|.|...|       :.:..|..:| ..|||           ||.           .
Mosquito   730 LSEEEEEELLEKLANR-------HYYSYTAALGVTVGVGCLLLLLNMLIFAGIYYQRDRTKRKSQ 787

  Fly   783 TGTAGGVRNGGGTRAGTVSGFGGTLGTVEELLDPVAGQFEPS 824
            |..:.|...|.|..:||.:...|:.||.:|...|:.....||
Mosquito   788 TSQSSGTVGGSGVTSGTSASLSGSNGTPDESEIPLTSIPSPS 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	139/561 (25%)
LOC1280747	XP_061513099.1	None