Protein Alignment CG12869 and Gli

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: XP_061510245.1
• Gene: Gli / 1277780
• VectorBaseID: AGAMI1_001484
• Length: 973
• Species: Anopheles gambiae
• Alignment Length: 868
• Identity: 197/868 - (22%)
• Similarity: 312/868 - (35%)
• Gaps: 269/868 - (30%)

  Fly    46 DGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIYDESSDGSMPR 110
            |...|....|||||||..|.:|.||.|.:....: :.:||....|.|||...  |..::.|..
Mosquito   176 DRIMGKCSTFLGIPYALPPTHEGRFKPPRQHRGW-QLVQAVDYGPACPQPVQ--YTGATKGIR-- 235

  Fly   111 SVSTDEDCLYLNIWTPES----GMRYGKLPIVVIVTGEEFAYDWPRNRINGLDLAG-EGIVVVSV 170
              ..|||||||||::|.:    ..||   |:::.:.|.||... ..|...|..||. ..:|||:.
Mosquito   236 --DMDEDCLYLNIFSPNTQAGVAQRY---PVMIYIHGGEFVRG-ASNTFPGHMLAAFYDVVVVTF 294

  Fly   171 QYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVA 235
            .||....|:||.|::  |.|||||:.|..||:||:..|.::|.|:.:.|||.|.|:|||...|:.
Mosquito   295 NYRLGALGFLSTGDE--NSPGNYGILDQIMAVRWVYENIESFNGDRNSITLFGPGAGGASAGLLM 357

  Fly   236 TLEDSSQVKQLVLMSPGPIMRALGQNH----------QKWIVE-TGQVLVQKLGCQFEEAQRRQL 289
            .   :.|.|.:|       .|.:||:.          .||..: |.:|..|.:||..|.:.:  :
Mosquito   358 V---APQTKDIV-------TRVIGQSGSALADWALIVDKWRAQNTSRVFAQNVGCSIETSWK--M 410

  Fly   290 MGCLRRKSREDLLRAYESVYNHGN-------GSSQLGVIL------------------------- 322
            :.|:|..         .|.|..||       |....|.:|
Mosquito   411 VNCMRNG---------RSSYELGNAEFPPHVGLFPWGPVLENNFTFPGDSWYEGWSERDWHFLAE 466

  Fly   323 -PEGLPLEQRLRNKTLPPVLLGITSNEGAFLQDYWLDVAREGQVALHKYINHTLLPNVMRALESV 386
             ||.| :.:|..|:.| ..:.|:|..|.||:      :.....:|.:..::.......:|.|
Mosquito   467 TPESL-IRRRHFNRGL-HYMSGVTLQEAAFV------ITGNKSLAPYFEVDERFFDQKVREL--- 520

  Fly   387 GEESSTQLAAIRWRY---FNGKGEGVSHLLAGMQ-------------RLLSESLYELPYSRILEL 435
                     .:|:.|   .||..|.:.::.....             .|||:.||..|..::::|
Mosquito   521 ---------VLRYNYTLNLNGTYEAIKYMYTYWPDPKNTTFIREQYINLLSDFLYRAPTDKLIKL 576

  Fly   436 L--NGTTSYAYVFDHSHSMDMRGRRNL-FGGASHSSDLPLLLGPSLF--------QQIARRRFSG 489
            |  .....|:||.:.:    :.|.:.. :....|..:..||.|....        ::..|..::.
Mosquito   577 LVEQNVPVYSYVMNTT----IEGLKLAEWCKVPHDIEHYLLAGAPFMDVEFFPRRERFDRLMWTD 637

  Fly   490 EEEQLCRKIRGAFANFIKNGNPTPGRIYDGWLPYNKENPFVYSLGEQAKTPQTGSVDEAEVDKLL 554
            .:..:.......:::|.::|||||.::                ||             ...:|..
Mosquito   638 NDRNMSHFFMKTYSDFARHGNPTPTQV----------------LG-------------LYFEKAR 673

  Fly   555 RGETGAPGLDRSLSRSNRHDTYRAAPSNSYTASNQLDSGY-SNHLQMVYGFWQVLMPL------- 611
            .||         |...|.:.||.:....:|   .|.:|.: ..:|..|.|   ||:|.
Mosquito   674 NGE---------LKYLNLNTTYNSTIMMNY---RQTESAFWMEYLPTVVG---VLIPTYPPTTEF 723

  Fly   612 --EREEDLRGGGALGQRVRLLEASADAARYRQGFYAMLGLVCLLLACLCLCVYLLKRDPNAMRRR 674
              |.:|.|                      :..|:::.....:|:..:.:|         .|..|
Mosquito   724 WWEPKEPL----------------------QIAFWSLAAACLILMVLVVIC---------CMMWR 757

  Fly   675 SASSASD-CYSLXHKWFRWTTIFGGRKDEVPSTSGIANVESWRKGGRATKREQDGSGAVESGGGD 738
            ||...|| .|                 ||  :..|:.|.||    .|.|..|.:...|....|..
Mosquito   758 SAKRESDRLY-----------------DE--AVFGMDNPES----ERDTVMENNMLQAQPLRGQS 799

  Fly   739 GNLEGERREQVLNKQRTRRPRQLQPYDFKITHPIGGAGVGAGFGTGTAGGVRNGGGTRAGTVSGF 803
            ||:. |.|:              .|..:....|.||           .|.:|:........|:|.
Mosquito   800 GNIY-EYRD--------------SPSKYSKMPPDGG-----------GGSIRSPSSLGMTQVTGK 838

  Fly   804 GGTLGTVEELLDPVAGQFEPSVA 826
            .|..|:...|...::.:...|::
Mosquito   839 SGLTGSQSSLRSAISMKESSSIS 861

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	141/570 (25%)
Gli	XP_061510245.1	None