Protein Alignment CG12869 and Ces1g

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_067431.2
• Gene: Ces1g / 12623
• MGIID: 88378
• Length: 565
• Species: Mus musculus
• Alignment Length: 613
• Identity: 161/613 - (26%)
• Similarity: 264/613 - (43%)
• Gaps: 127/613 - (20%)

  Fly    14 LPILIHLSPYISAQQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSS 78
            ||.::|        ..|     |.::|..|..:|....|..|||:|:|:.|:..|||||.:|:..
Mouse    22 LPPVVH--------TVH-----GKVLGKYVTLEGFSQPVAVFLGVPFAKPPLGSLRFAPPEPAEP 73

  Fly    79 FNRTLQATTMQPLCPQ-------LANTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKLP 136
            ::.....|:..|||.|       ||....::..  .:|...|  ||||||||:||....:..:||
Mouse    74 WSFVKHTTSYPPLCYQNPEAALRLAELFTNQRK--IIPHKFS--EDCLYLNIYTPADLTQNSRLP 134

  Fly   137 IVVIVTGEEFAYDWPRNRINGLDLA-GEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQM 200
            ::|.:.|.....| ..:..:|:.|| .|.:|||.:|||..|:|:.|..::|..  ||:|..|...
Mouse   135 VMVWIHGGGLVID-GASTYDGVPLAVHENVVVVVIQYRLGIWGFFSTEDEHSR--GNWGHLDQVA 196

  Fly   201 ALRWIRRNADAFGGNPDHITLLGHGSGG--------APLALVATLEDSSQVKQLVLMSPGPIMRA 257
            ||.|::.|...|||||..:|:.|..:||        :|||  ..|...:..:..|:.:|....||
Mouse   197 ALHWVQDNIANFGGNPGSVTIFGESAGGESVSVLVLSPLA--KNLFHRAIAQSSVIFNPCLFGRA 259

  Fly   258 LGQNHQKWIVETGQVLVQKL----GCQFEEAQRRQLMGCLRRKSREDLLRA-----YESVYNHGN 313
                        .:.|.:|:    ||  :......::.|||:|:.::||..     :.:|...|:
Mouse   260 ------------ARPLAKKIAALAGC--KTTTSAAMVHCLRQKTEDELLEVSLKMKFGTVDFLGD 310

  Fly   314 GSSQL--------GVILPEGLPLEQRLRNKTL--PPVLLGITSNEGAF---------LQDYWLDV 359
            .....        ||:||:. | |:.|..|:.  .|.::||..:|..:         |.:..||.
Mouse   311 PRESYPFLPTVIDGVLLPKA-P-EEILAEKSFNTVPYMVGINKHEFGWIIPMFLDFPLSERKLDQ 373

  Fly   360 AREGQVALHKY----INHTLLPNVMRALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLL 420
            .....:....|    |:..|:|                 |||. :|..|. |..:.:......|:
Mouse   374 KTAASILWQAYPILNISEKLIP-----------------AAIE-KYLGGT-EDPATMTDLFLDLI 419

  Fly   421 SESLYELPYSRILELLN---GTTSYAYVFDHSHSMDMRGR-RNLFGGASHSSDLPLLLGPSLFQQ 481
            .:.::.:| |.|:...:   |..:|.|.:.:..|.....| :.|.|  .|:.:|..:.|....::
Mouse   420 GDIMFGVP-SVIVSRSHRDAGAPTYMYEYQYRPSFVSDDRPQELLG--DHADELFSVWGAPFLKE 481

  Fly   482 IARRRFSGEEEQLCRKIRGAFANFIKNGNPTPGRIYDGWLPYNKENPFVYSLGEQAKTPQTGSVD 546
            .|    |.||..|.:.:...:|||.:||||. |.....|..|:::..:: .:|..|:...  .:.
Mouse   482 GA----SEEEINLSKMVMKFWANFARNGNPN-GEGLPHWPEYDQKEGYL-QIGVPAQAAH--RLK 538

  Fly   547 EAEVD---KLLRGETGAPGLDRSLSRSN 571
            :.|||   :|...||.    :||..|.:
Mouse   539 DKEVDFWTELRAKETA----ERSSHREH 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	149/565 (26%)
Ces1g	NP_067431.2	COesterase	24..545	CDD:278561	153/588 (26%)
		Aes	<121..>239	CDD:223730	42/122 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910