Protein Alignment CG12869 and clt

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Alignment Length: 646
• Identity: 153/646 - (23%)
• Similarity: 256/646 - (39%)
• Gaps: 184/646 - (28%)

  Fly    23 YISAQQTHIKLEQGDLIGLKVFPDGTRGAVY-AFLGIPYAQAPINELRFAPAKPSSSFNRTLQAT 86
            :.|:.:..:.::||.|:|.:  .....|..| :|||:|||:.|:.||||...:|...|.:
  Fly    14 FCSSMKVKVPVKQGVLVGRQ--KKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQK----- 71

  Fly    87 TMQPL-CPQLANTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKLPIVVIVTGEEFAYDW 150
              |.| |.:..|..|...   .....|:..||||:||::.|:.......||::|.:.|..|.:.
  Fly    72 --QELDCSKEGNVSYQRD---PFTLEVAGSEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFG- 130

  Fly   151 PRNRING-------LDLAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRN 208
                 ||       ..|..:.::||::.||....|:|||.|:  .:.||.||.|.::||.|::.|
  Fly   131 -----NGNSDFHFPAKLMEQEVIVVTLNYRLGALGFLSLPEE--GIHGNMGLKDQRLALEWVQEN 188

  Fly   209 ADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQNHQKWIVET---- 269
            ..:|.|:|:::||.|..:||:.:.|......:.::....:|..|..       :.:|:.:.
  Fly   189 IASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQSGTA-------NMEWVFQNEAPA 246

  Fly   270 -GQVLVQKLG--------------CQFEEAQRRQLMGCLRR-----KSREDLLRAYESVYNHGNG 314
             .:.|.:.||              .|.|:|....::....:     :.|..|..|::.|....:.
  Fly   247 KTRRLAELLGGGDFGGDSKALLTFLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSS 311

  Fly   315 SSQLGVILPEGLPLEQ---RLRNKT----LPPVLLGITSNEGAF--------LQDYWLDVAREGQ 364
            ..:.         |||   .|.:|.    ..||::|..|.||..        |:.|..|:||
  Fly   312 PDRF---------LEQDIMELMHKKDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLAR--- 364

  Fly   365 VALHKYINHTLLPNVMRALESVGEESSTQLAAIRWRYFNGKG---EGVSHLLAGMQRLLSESLYE 426
                      |:|..: .|:....|:....:.||..:|||:.   |.:.:|:    .|.|:..:.
  Fly   365 ----------LVPRNL-VLDPQAPEAQEAASDIRAFFFNGQALSKENMDNLV----DLFSDYHFS 414

  Fly   427 LPYSRILELLNG--TTSYAYVFDHSHSMDMRGRRNLF---------GGASHSSDLPLLLGPSLFQ 480
            :...|.:|:...  |.|..|.:    .:|..|.|||:         .|.:|:.|:..     |||
  Fly   415 MDLQRAVEIHASCQTQSPLYFY----RLDYVGGRNLYKKIFQNEDLRGVAHADDICY-----LFQ 470

  Fly   481 QIARRRFSGEE-----------EQLCRKIRGAFANFIKNGNPTPGRIYDGWLPYNKENPFVYSLG 534
                  .:|:|           |:||.    .:|||.::|.|:|     .|.|
  Fly   471 ------MAGDETEMNRDDLMVTERLCE----MWANFARDGKPSP-----IWKP------------ 508

  Fly   535 EQAKTPQTGSVDEAEVDKLLRGETGAPGLDRSLSRSNRHD---------TYRAAPSNSYTA 586
              .|.|..|  :..::|.||        :||.|...:..|         .||...|.::.|
  Fly   509 --VKKPHNG--EPIQLDCLL--------IDRELKMCSNPDGERMDFWRSMYRRYRSENFEA 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	139/586 (24%)
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	148/622 (24%)