Protein Alignment CG12869 and Ces1d

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_444430.2
• Gene: Ces1d / 104158
• MGIID: 2148202
• Length: 565
• Species: Mus musculus
• Alignment Length: 558
• Identity: 149/558 - (26%)
• Similarity: 250/558 - (44%)
• Gaps: 103/558 - (18%)

  Fly    35 QGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQ--LAN 97
            :|.::|..|..:|....|..|||:|:|:.|:..|||||.:|:..::.....|:..|:|.|  :..
Mouse    30 KGKVLGKYVNLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCSQDAVGG 94

  Fly    98 TIYDE---SSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKLPIVV------IVTGEEFAYDWPRN 153
            .:..|   :...::|...|  ||||||||:||....:..:||::|      :|.|....||
Mouse    95 QVLSELFTNRKENIPLQFS--EDCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVGGASTYD---- 153

  Fly   154 RINGLDL-AGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPD 217
               ||.| |.|.:|||::|||..|:|:.|.|::|..  ||:|..|...||||::.|...|||||.
Mouse   154 ---GLALSAHENVVVVTIQYRLGIWGFFSTGDEHSR--GNWGHLDQVAALRWVQDNIANFGGNPG 213

  Fly   218 HITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQN-HQKWIVETGQVLVQKL---- 277
            .:|:.|..:||..::             ::::||      |.:| ..:.|.|:|..|...|
Mouse   214 SVTIFGESAGGFSVS-------------VLVLSP------LAKNLFHRAISESGVSLTAALITTD 259

  Fly   278 ------------GCQFEEAQRRQLMGCLRRKSREDLLRAYESVYNH-----GNGSSQL------- 318
                        ||  :......::.|||:|:.::||.....:...     ||.....
Mouse   260 VKPIAGLVATLSGC--KTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVI 322

  Fly   319 -GVILPEGLPLEQRLRNKTLP--PVLLGITSNEGAF----LQDYWLDVAREGQVALHKYINHTLL 376
             ||:||:. | |:.|..|:..  |.::||...|..:    |..|.|   .||:  |.:...::||
Mouse   323 DGVVLPKA-P-EEILAEKSFSTVPYIVGINKQEFGWIIPTLMGYPL---AEGK--LDQKTANSLL 380

  Fly   377 PNVMRALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILELLN---G 438
            ......|:.    |...:..:..:|..|. :.::......|.|:::.::.:| |.|:...:   |
Mouse   381 WKSYPTLKI----SENMIPVVAEKYLGGT-DDLTKKKDLFQDLMADVVFGVP-SVIVSRSHRDAG 439

  Fly   439 TTSYAYVFDHSHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRGAFA 503
            .::|.|.|::..|.....|.....| .|..::..:.|....:..|    |.||..|.:.:...:|
Mouse   440 ASTYMYEFEYRPSFVSAMRPKAVIG-DHGDEIFSVFGSPFLKDGA----SEEETNLSKMVMKFWA 499

  Fly   504 NFIKNGNPTPGRIYDGWLPYNKENPFVYSLGEQAKTPQ 541
            ||.:||||..|.: ..|..|:::..:: .:|...:..|
Mouse   500 NFARNGNPNGGGL-PHWPEYDQKEGYL-KIGASTQAAQ 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	148/556 (27%)
Ces1d	NP_444430.2	COesterase	24..545	CDD:278561	149/558 (27%)
		Aes	<121..>239	CDD:223730	47/145 (32%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910