Protein Alignment CG12869 and Ces2a

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_598721.1
• Gene: Ces2a / 102022
• MGIID: 2142491
• Length: 558
• Species: Mus musculus
• Alignment Length: 531
• Identity: 151/531 - (28%)
• Similarity: 240/531 - (45%)
• Gaps: 80/531 - (15%)

  Fly    13 LLPILIHLSPYISA---QQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAK 74
            ||.:|.|:....||   :.||    :|.:.|..|....|:..|:||||||:|:.|:..|||||.:
Mouse    17 LLLLLQHVHGQDSASPIRNTH----RGQVRGSFVHVKDTKSGVHAFLGIPFAKPPVGLLRFAPPE 77

  Fly    75 PSSSFNRTLQATTMQPLC--PQLANTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKLPI 137
            ....::.....|:...:|  |.:.| :.|......:...:|..||||||||:||........||:
Mouse    78 DPEPWSGVRDGTSQPAMCLQPDIMN-LEDAKEMNLILPPISMSEDCLYLNIYTPTHAQEGSNLPV 141

  Fly   138 VV------IVTGEEFAYDWPRNRINGLDLAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLS 196
            :|      :|.|..     ..|.::.| .|.|.||:|::|||..:.|:.|.|:||..  ||:|..
Mouse   142 MVWIHGGGLVVGSA-----SMNDVSKL-AATEEIVIVAIQYRLGVLGFFSTGDQHAR--GNWGYL 198

  Fly   197 DVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQN 261
            |...||||:::|...||||.|.:|:.|..:||..:        ||.:  |..||.|....|:.|:
Mouse   199 DQVAALRWVQKNIAYFGGNRDRVTIFGVSAGGTSV--------SSHI--LSPMSKGLFHGAIMQS 253

  Fly   262 H----QKWIVETGQVLVQKL----GCQFEEAQRRQLMGCLRRKSREDLLRAYESVYNHGNGSSQL 318
            .    ...|.:|.:|:.:.:    ||:..:::  .|:.|||.||::::| |...|:.
Mouse   254 GVALLPDLISDTSEVVYKTVANLSGCEATDSE--ALIHCLRAKSKQEIL-AINQVFK-------- 307

  Fly   319 GVILP-----EGLPL--EQRLRNKTLPPV--LLGITSNEGAFLQDYWLDVAREGQVALHKYINHT 374
              ::|     |.||.  ::.|.:....||  ::|:.::|..     |......|...:.|.|...
Mouse   308 --MIPAVVDGEFLPKHPQELLTSMDFHPVPSIIGVNTDECG-----WGVPMFMGLDHIIKNITRE 365

  Fly   375 LLPNVMR---ALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILELL 436
            .||.|::   |...:..|.|..|.    ..:.|..|....|.|..:.:|.:.::.:|..::....
Mouse   366 TLPAVLKNTAARMMLPPECSHLLV----EEYMGDTEDPETLQAQFREMLGDFMFVIPALQVAHFQ 426

  Fly   437 NGTTS-YAYVFDHSHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRG 500
            ..... |.|.|.|..|. ::..|.....|.|..|:..:.|..|:..  ....:.|||.|.|.:..
Mouse   427 RSQAPVYFYEFQHLSSF-IKHVRPSHVKADHGDDVAFVFGSYLWDM--NLDLTEEEELLKRMMMK 488

  Fly   501 AFANFIKNGNP 511
            .:|||.:||||
Mouse   489 YWANFARNGNP 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	145/514 (28%)
Ces2a	NP_598721.1	COesterase	30..537	CDD:395084	146/518 (28%)