Protein Alignment CG12869 and Ces2

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001177298.1
• Gene: Ces2 / 100910144
• RGDID: 6504334
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 650
• Identity: 169/650 - (26%)
• Similarity: 270/650 - (41%)
• Gaps: 148/650 - (22%)

  Fly     2 W-NALRIQQILRLLPILIHL----SPYIS-AQQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPY 60
            | ||:    :..||.:|||:    ||..| .:.||....||.|..:|    .|:..|:.|||||:
  Rat     9 WLNAV----LFGLLLLLIHVQGQDSPESSPIRTTHTGQVQGKLDHVK----DTKAGVHTFLGIPF 65

  Fly    61 AQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIYDESSDGSMP---RSVSTDEDCLYLN 122
            |:.|:..|||||.:|...::....||:...:|.|..: |.||.....|.   .|:|..|||||||
  Rat    66 AKPPVGPLRFAPPEPPEPWSGVRDATSQPAMCLQNLD-ILDEVGLLDMKMILSSISMSEDCLYLN 129

  Fly   123 IWTPESGMRYGKLPIVV------IVTGEEFAYDWPRNRINGLDLAGEGIVVVSVQYRNNIYGWLS 181
            ::.|........||::|      :|.|....||.....:|      |.:|||::|||..:.|:.|
  Rat   130 VYAPAHAREGSNLPVMVWIHGGALVVGMASMYDGSLLTVN------EDLVVVTIQYRLGVLGFFS 188

  Fly   182 LGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQL 246
            .|::|..  ||:|..|...||||:::|...|||||:.:|:.|..:||..:        ||.|
  Rat   189 TGDEHAR--GNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGESAGGTSV--------SSHV--- 240

  Fly   247 VLMSP-------GPIMR---ALGQNHQKWIVETGQVLVQKL-GCQFEEAQRRQLMGCLRRKSRED 300
              :||       |.||.   ||..:......||....|.|| ||:..:::  .|:.|||.||..:
  Rat   241 --ISPMSQGLFHGAIMESGVALLPDLISETSETVSTTVAKLSGCEAMDSE--ALVRCLRAKSGAE 301

  Fly   301 LL---RAYESVYNHGNGSSQLGVILPEGLPL--EQRLRNKTLPPV--LLGITSNEGAFLQDYWLD 358
            :|   :.::.:         ..|:..|.||.  ::.|.::...||  ::|:.::|..
  Rat   302 ILVINKVFKMI---------PAVVDGEFLPRHPKELLASEDFHPVPSIIGVNTDEYC-------- 349

  Fly   359 VAREGQVALHKYINHTLLPNVMRALESVGEESSTQLAAI-----------------RWRYFNGKG 406
                           ..:|.||...:.:.|.|...|.|:                 ....:.|..
  Rat   350 ---------------CTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPPECGDLLMEEYMGNT 399

  Fly   407 EGVSHLLAGMQRLLSESLYELPYSRILELLNG-TTSYAYVFDHSHSMDMRGRRNLFGGASHSSDL 470
            :....|......::.:.|:.:|..::...... ...|.|.|.|:.|. .:..|.....|.|:.::
  Rat   400 DDSQTLQIQYTEMMGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSY-FKNVRPPHVKADHADEV 463

  Fly   471 PLLLGPSLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNPTPGRIYDGWLPYNKENPFVYSLGE 535
            |.:.| |.|..: :..|:.||..|.|::...:|||.:.|||            |.|.
  Rat   464 PFVFG-SFFSGM-KLDFTEEERLLSRRMMKYWANFARQGNP------------NSEG-------- 506

  Fly   536 QAKTPQTGSVDEAEVDKLLRGETGAPGLDRSLSRSNRHDTYRAAPSNSYTASNQLDSGYSNHLQM 600
               .|...::|..|  :.|:.:| .|.:||:|.........:..|..    ..:|:....||.::
  Rat   507 ---LPYWPALDHDE--QYLQLDT-HPAVDRALKARRLQFWTKTLPQK----IEELNGAQKNHAEL 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	145/558 (26%)
Ces2	NP_001177298.1	COesterase	32..540	CDD:395084	155/596 (26%)