Protein Alignment CG12869 and bche

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: XP_002931610.1
• Gene: bche / 100495889
• XenbaseID: XB-GENE-980117
• Length: 602
• Species: Xenopus tropicalis
• Alignment Length: 584
• Identity: 158/584 - (27%)
• Similarity: 242/584 - (41%)
• Gaps: 113/584 - (19%)

  Fly    31 IKLEQGDLIG--LKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCP 93
            :..:.|.:.|  :.||    .|.:.||||||||:.||.:|||....|...::....|:.....|.
 Frog    33 VDTKYGKVTGVQISVF----SGIITAFLGIPYAEPPIGDLRFKKPVPHKPWSEIWNASQYGNSCY 93

  Fly    94 QLANTIYDESSDGSM--PRSVSTDEDCLYLNIWTPESGMRYGKLPIVVIVTGEEFAYDWPRNRIN 156
            |..:.|:...|...|  | :....|||||||||.|....|  ...::|.:.|..|     ....:
 Frog    94 QTVDQIFPGFSGAEMWNP-NTQLSEDCLYLNIWIPTPKPR--NASVMVWIYGGSF-----ETGTS 150

  Fly   157 GLDL-------AGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGG 214
            .|||       ..|.::|||:.||....|:|:. ..:...|||.||.|.::||:|:..|..||||
 Frog   151 SLDLYDGKFLARTERVIVVSMNYRLGALGFLAF-PGNNEAPGNVGLFDQRLALQWVYENIAAFGG 214

  Fly   215 NPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQN---HQKWIVET------- 269
            ||..||:.|..:|||          |.....|...|.|...||:.|:   :..|.|.|
 Frog   215 NPKSITIFGESAGGA----------SVSYHMLSPKSHGFFTRAIMQSATANAPWAVITKAEASNR 269

  Fly   270 GQVLVQKLGCQFEEAQRRQLMGCLRRKSREDLLRAYESVYNHGN---------GSSQLGVILPEG 325
            ...|...|.|.:.  ...:::.|||.||.|::.....||..|.:         ......:.:||.
 Frog   270 ALTLANLLNCFYR--NETEIIACLRNKSPEEIFEKAVSVLPHRSVIEVNFPPTVDGDFLIEMPEI 332

  Fly   326 LPLEQRLRNKTLPPVLLGITSNEGAFLQDYWLDVAREGQVALHK-YINHTLLPNVMRALESVGEE 389
            |....:|:.||  .:|.|:..:||::...|.|    .|....|: :||.|.....::    :...
 Frog   333 LMQLGQLKKKT--QILTGVNKDEGSYFLVYGL----PGFSKDHESFINRTQFHKSVK----LAFP 387

  Fly   390 SSTQLA--AIRWRYFNGKGE-GVSHLLAGMQRLLSESLYELPYSRILELLN--------GTTSYA 443
            .:|:||  ::.:.|.|.:.| ..||....|..::.:      |:.|..||.        |..:|.
 Frog   388 KATELAIDSVLFHYTNWEDEQNPSHNRDAMDDIVGD------YNFICPLLEFTKWNSELGNNAYL 446

  Fly   444 YVFDH-SHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRGAFANFIK 507
            |.|.| |..:...|    :.|..|..::..:.|..:::   |..::..||.|.|.:...:|||.|
 Frog   447 YYFHHRSSKLTWPG----WMGVMHGYEIEFVFGIPMYR---RLNYTKAEETLSRTLMRYWANFAK 504

  Fly   508 NGNPTPGRIYDG-WLPYNKENPFVYSLG-EQAKTPQ--------------------TGSVDEAE 549
            .|||...:..:. |..:..:......|| |.:||.:                    ||::||.|
 Frog   505 TGNPNGAQSSENRWPVFTLDEQHYLMLGTEDSKTNRKMRAKQCRFWNNFYPKVLQITGNIDEVE 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	153/554 (28%)
bche	XP_002931610.1	COesterase	32..550	CDD:395084	153/564 (27%)
		AChE_tetra	565..599	CDD:430146	3/4 (75%)