Protein Alignment CG12869 and ces2.8

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: XP_002943465.3
• Gene: ces2.8 / 100494149
• XenbaseID: XB-GENE-6467125
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 578
• Identity: 160/578 - (27%)
• Similarity: 260/578 - (44%)
• Gaps: 112/578 - (19%)

  Fly    13 LLPILI----HLSPYISAQQTHIKL---EQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRF 70
            |:.:|:    .|..|.:.|....||   :.|.|:|..|...||..:|:||:|:|:|:.|...||:
 Frog     4 LIKVLLLCCATLEIYGTGQNDVKKLVTTKYGQLLGKTVGVKGTDRSVHAFMGVPFAKPPTGPLRY 68

  Fly    71 APAKPSSSFNRTLQATTMQPLCPQLANTIYDESSDGSMPRSVS----------TDEDCLYLNIWT 125
            |..:|...::...:||....:|.|         :...|.:||:          ..|||||||::|
 Frog    69 ADPQPPEPWSSVREATAPPSMCIQ---------NPAIMEKSVTVFKANSVLPPVSEDCLYLNVFT 124

  Fly   126 PESGMRYGKLPIVV------IVTGEEFAYDWPRNRINGLDLA-GEGIVVVSVQYRNNIYGWLSLG 183
            |.......|||::|      :|.|....||       |..|: .|.:|:||||||..:.|:.|.|
 Frog   125 PAGREENAKLPVMVFIHGGGLVIGYASLYD-------GSALSVYENVVMVSVQYRLGLLGFFSTG 182

  Fly   184 EQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVL 248
            :  :.||||.|..|...||:|::.|..||||:|..:||.|..:||        |..|:.:  |..
 Frog   183 D--KEVPGNLGFLDQVAALQWVQENIKAFGGDPQSVTLFGESAGG--------LSVSAHI--LSP 235

  Fly   249 MSPGPIMRALGQN----------HQKWIVETGQVLVQKL-GCQFEEAQRRQLMGCLRRKSREDLL 302
            :|.....||:.::          |:...|..|:.|:..: ||...     .|:.||:.|:.:::|
 Frog   236 LSKNLFHRAIAESGVAVFPNLMVHKTEDVLFGRDLIANISGCDLP-----LLLNCLKEKTEDEIL 295

  Fly   303 RAYESVYNHGNGSSQL-----GVILPEGLPLEQRLRNKTLPPV--LLGITSNEGAFLQDYWLDVA 360
            ....::     |.:.|     ||.||:  |.|:.|..|...||  ::|:.::|..:.....|:::
 Frog   296 AITLAM-----GFTILPACVDGVFLPK--PAEEILAAKESNPVPFIIGVNNHEFGWEIPMSLNIS 353

  Fly   361 --REG--QVALHKYINHTLLPNVMRALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLS 421
              |.|  :..:...:..::|.....|:.|:.||           ||....:.: .:......|..
 Frog   354 GFRGGMEKKDIEALLQFSILHLDSNAISSIMEE-----------YFGDTNDQI-EIRNNFLELGG 406

  Fly   422 ESLYELPYSRILELL--NGTTSYAYVFDHSHSMDMRGRRNLFGGASHSSDLPLLL-GPSLFQQIA 483
            :.|:.:|..|..:..  :|...|.|.|.|..|: ....::.|..|.|..:|..:| ||.|...:.
 Frog   407 DMLFVIPALRTAKYHRDSGLPVYFYEFQHRPSL-YENSKDDFVKADHGDELYFVLGGPFLNGDVT 470

  Fly   484 RRRFSG----EEEQLCRKIRGAFANFIKNGNPT-PGRIYDGWLPYNKENPFVYSLGEQ 536
               |.|    ||:.|.|||...::||.:||:|. ||  ...||.|:::..::....||
 Frog   471 ---FQGDGTDEEKVLSRKIMKYWSNFARNGDPNGPG--LTEWLKYDEDEDYLEICLEQ 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	156/560 (28%)
ces2.8	XP_002943465.3	COesterase	29..537	CDD:395084	153/553 (28%)