Protein Alignment CG12869 and ache

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: XP_002940088.1
• Gene: ache / 100490673
• XenbaseID: XB-GENE-923160
• Length: 600
• Species: Xenopus tropicalis
• Alignment Length: 595
• Identity: 147/595 - (24%)
• Similarity: 232/595 - (38%)
• Gaps: 174/595 - (29%)

  Fly    52 VYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIYD-----ESSDGSMPRS 111
            |.||||||:|:.|::::||..::|...:.....||.....|.|..:|:|.     |..:.:.|.|
 Frog    50 VSAFLGIPFAEPPVDKMRFRRSEPKKPWTDVWDATAYPNACYQYFDTLYPGFPGMEMWNPNRPMS 114

  Fly   112 VSTDEDCLYLNIWTPESGMRYGKLPIVVIVTGEEF--------AYDWPRNRINGLDLA-GEGIVV 167
                |||||||||.|..  |.....::|.:.|..|        .||       |..|. .|.::|
 Frog   115 ----EDCLYLNIWVPHP--RPSNATVMVWIYGGGFYSGSSSLDVYD-------GRYLCHAENVIV 166

  Fly   168 VSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLA 232
            ||:.||...:|:|:|.....:.|||.||.|.::||:|::.|...|||:|..:|:.|..:|...:.
 Frog   167 VSMNYRVGAFGFLTLTPGSVDAPGNVGLFDQRLALQWVQDNIAFFGGDPRTVTIFGESAGAVSVG 231

  Fly   233 LVATLEDSSQVKQLVLMSPGP----IMRAL--GQNHQKWIVETGQVLVQKLGCQFEEAQRR---- 287
                         :.::|||.    ...||  |..:..|...|.|           ||:||
 Frog   232 -------------MHVLSPGSHHLFSKAALQSGSPNTPWATITPQ-----------EARRRTELL 272

  Fly   288 ------------QLMGCLRRKSREDLLRAYESVYNHGNGSSQLGVILPEGLPLEQRLRNKTLP-- 338
                        :|:.|||.|..::|:....||                 ||.....|...:|
 Frog   273 GKFLDCRMGNDTELLNCLRVKQPQELIDHEFSV-----------------LPAPSVFRFAFVPVP 320

  Fly   339 ---------------------PVLLGITSNEGAFLQDY---WLDVAREGQVALHKYINHTLLPNV 379
                                 |:::|:..|||::...|   ......|..:...:::....:
 Frog   321 DADFFPEPPEILMNMGRFKPCPLIMGVNQNEGSYFLLYGAPGFSKNNESLITREEFLGGVKM--- 382

  Fly   380 MRALESVGEESSTQLAAIRWRYFNGKGE--GVSHLLAGMQRLLSES--LYELPY--SRILELLNG 438
                 ||.:.:...|.|:..:|.:...|  ||.:..| |.:|:.:.  :..|.|  .::.|  .|
 Frog   383 -----SVPQANDIALEAVVMQYTDWADEHAGVKNREA-MDQLVGDHNVICPLTYFAGKVAE--TG 439

  Fly   439 TTSYAYVFDHSHSMDMRGRRNL----FGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIR 499
            ...|.|.|||..|       ||    :.|..|..::..:.|..|   .|...::.:||.|.|::.
 Frog   440 NRVYTYFFDHRAS-------NLAWPQWMGVPHGYEIEFVFGLPL---DANLNYTPQEEALSRRMM 494

  Fly   500 GAFANFIKNGNPTPGRIYDG----WLPYN---------KENPFVYSLGEQAKT--------PQ-- 541
            ..:|||.:.|:|..|.  |.    |..|.         ...|:....|.:.:|        |:
 Frog   495 RYWANFARTGDPNEGN--DAHQPRWPLYTASEQRYMALNNKPYQELQGIRVQTCMFWNRFLPKLL 557

  Fly   542 --TGSVDEAE 549
              |.::||||
 Frog   558 NITDNIDEAE 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	141/581 (24%)
ache	XP_002940088.1	COesterase	31..549	CDD:395084	141/575 (25%)
		AChE_tetra	564..597	CDD:430146	4/4 (100%)