Protein Alignment CG12869 and nlgn3

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: XP_012823589.1
• Gene: nlgn3 / 100329188
• XenbaseID: XB-GENE-977261
• Length: 843
• Species: Xenopus tropicalis
• Alignment Length: 693
• Identity: 162/693 - (23%)
• Similarity: 268/693 - (38%)
• Gaps: 159/693 - (22%)

  Fly    19 HLSPYISAQQTHIKLEQGDLIGLKV-FPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRT 82
            |...|.....||    .|.|.|.:| .|....|.|..:||:|||..|:.|.||.|.:|..|::..
 Frog    30 HAQVYSQTVNTH----YGKLRGTRVPLPSEILGPVDQYLGVPYAAPPVGEKRFLPPEPPPSWSGI 90

  Fly    83 LQATTMQPLCPQLANTIYDESSDGSMP----RSVST--------DEDCLYLNIWTPESGMR---- 131
            ..||...|:|||   .|.:...|..||    .::.|        .||||||||:.|...::
 Frog    91 RNATHFSPVCPQ---NIQNAVPDIMMPVWFTSNLDTVTGYLQEQSEDCLYLNIYVPTEDVKRISK 152

  Fly   132 --------------------------------------YGKLPIVVIVTGEEFAYDWPRNRINGL 158
                                                  .|..|::|.:.|..: .:...|.|:|.
 Frog   153 ECVRKPNKKICRKGGPSAKKQGEELSDNDEDEEGDIRDTGAKPVMVYIHGGSY-MEGSGNMIDGS 216

  Fly   159 DLAGEG-IVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLL 222
            .||..| :||:::.||..:.|:||.|:|  ...|||||.|...||||:..|...|||:|..||:.
 Frog   217 VLASYGNVVVITLNYRVGVLGFLSTGDQ--AAKGNYGLLDQIQALRWVSENVAFFGGDPHRITVF 279

  Fly   223 GHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQNHQKWIVETGQVLVQKLGCQFEEAQRR 287
            |.|.|.:.::|:.....|..:.|..::..|..:.:...|:|.  |:..::|.:|:||...:..
 Frog   280 GSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQP--VKYTRLLAEKVGCNVLDTV-- 340

  Fly   288 QLMGCLRRKSREDLLR--AYESVYNHGNGSSQLGVILPEGLPLEQRLRNKTLPPVLLGITSNEGA 350
            .::.|||:||.::|:.  ...:.|:...|....|.::|:.            |.:|:    .:|.
 Frog   341 DMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDD------------PEILM----EQGE 389

  Fly   351 FLQ-DYWLDVAR-EGQVALHKYINHTL--------------LPNVMRALESVGEESSTQLAAIRW 399
            ||. |..|.|.: ||.    |::.:.:              :.|.:..|....|...|....|::
 Frog   390 FLNYDIMLGVNQGEGL----KFVENVVDAEDGVSGSDFDYSVSNFVDNLYGYPEGKDTLRETIKF 450

  Fly   400 RYFN-GKGEGVSHLLAGMQRLLSESLYELP--YSRILELLNGTTSYAYVFDHSHSMDMRGRRNLF 461
            .|.: ...:........:..|.::..:..|  .:..|....|:.:|.|.|.| |...:  .:..:
 Frog   451 MYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYH-HCQSL--MKPAW 512

  Fly   462 GGASHSSDLPL-----LLGPS-LFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNP--------- 511
            ..|:|..::|.     ::||: ||.    ..||..:..|...:...:.||.|.|:|
 Frog   513 ADAAHGDEVPYVFGVPMVGPTDLFP----CNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTK 573

  Fly   512 ---TPGRIYD--GWLPYNKENPFVYSLGEQAKTPQTGSVDEAEVDKLLRGETGAPGLDRSLSRSN 571
               |....::  .|..||..:.....:|.:.:..     |.....|:...:...|.|      .|
 Frog   574 FIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVR-----DHYRATKVAFWKHLVPHL------YN 627

  Fly   572 RHDTYRAAPSNSYTASN----QLDSGYSNHLQMVYGFWQVLMP 610
            .||.:.      ||::.    ..|:..::|:......|....|
 Frog   628 LHDMFH------YTSTTTKVPPSDTTQNSHITRRPKVWDTKRP 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	147/610 (24%)
nlgn3	XP_012823589.1	COesterase	31..618	CDD:278561	150/632 (24%)
		Aes	<195..>302	CDD:223730	40/109 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910