DRSC/TRiP Functional Genomics Resources

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Protein Alignment LamC and Vim

DIOPT Version :9

Sequence 1:NP_001260974.1 Gene:LamC / 36615 FlyBaseID:FBgn0010397 Length:640 Species:Drosophila melanogaster
Sequence 2:NP_112402.1 Gene:Vim / 81818 RGDID:621646 Length:466 Species:Rattus norvegicus


Alignment Length:472 Identity:138/472 - (29%)
Similarity:228/472 - (48%) Gaps:91/472 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 VTLNTR-----------VSRASTSTPVGGA----STSSRVGATSP-----------------TSP 38
            ||.:||           .||:..|:..|||    |::.|:.::.|                 .:.
  Rat    31 VTTSTRTYSLGSALRPSTSRSLYSSSPGGAYVTRSSAVRLRSSMPGVRLLQDSVDFSLADAINTE 95

  Fly    39 TRTSRQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAA 103
            .:.:|..||.|||.||||.|.|||::|.||.:|..|..||   :....:..|.|..:||:|:...
  Rat    96 FKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAEL---EQLKGQGKSRLGDLYEEEMREL 157

  Fly   104 RKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLA 168
            |:.:|:...:||::|:       |.|:|             ||:..||                 
  Rat   158 RRQVDQLTNDKARVEV-------ERDNL-------------AEDIMRL----------------- 185

  Fly   169 DRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTET 233
             |:|.:::    .|:.|.....|...|:.::..:|||:|||.:.:||:||:||..::|.:|:.|.
  Rat   186 -REKLQEE----MLQREEAESTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHDEEIQEL 245

  Fly   234 RSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQ 298
            :::.|.:..:||..:|:   ..|..:|:::|.|||.....|.:|.|..|.::..:|..||||...
  Rat   246 QAQIQEQHVQIDVDVSK---PDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNND 307

  Fly   299 GSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRM 363
            ....|.:|....|.::..|..::..|:.||..|..::||:|.....|...:...|..|:.|:|.|
  Rat   308 ALRQAKQESNEYRRQVQSLTCEVDALKGTNESLERQMREMEENFALEAANYQDTIGRLQDEIQNM 372

  Fly   364 RDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPG------RPTTDSGISSNGSH 422
            ::|||..|:|||.|:::|::||:|||.|.|||.|||.|:::..|.      |.|....:....:|
  Rat   373 KEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLNLRETNLESLPLVDTH 437

  Fly   423 -----LTASASSRSGRV 434
                 |..:..:|.|:|
  Rat   438 SKRTLLIKTVETRDGQV 454

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LamCNP_001260974.1 Filament 45..401 CDD:278467 115/355 (32%)
ATP-synt_B <67..>142 CDD:304375 19/74 (26%)
MreC <178..>224 CDD:302802 16/45 (36%)
LTD 473..574 CDD:279300
VimNP_112402.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..33 1/1 (100%)
Head 2..95 13/63 (21%)
Filament_head 14..101 CDD:282575 13/69 (19%)
Coil 1A 96..131 18/34 (53%)
Filament 102..410 CDD:278467 115/355 (32%)
Linker 1 132..153 6/23 (26%)
DUF4559 <153..257 CDD:291771 35/145 (24%)
Coil 1B 154..245 32/132 (24%)
Linker 12 246..268 5/24 (21%)
Coil 2 269..407 49/137 (36%)
[IL]-x-C-x-x-[DE] motif. /evidence=ECO:0000250|UniProtKB:P08670 326..329 1/2 (50%)
Tail 408..466 10/47 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0977
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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