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Protein Alignment LamC and VIM

DIOPT Version :9

Sequence 1:	NP_001260974.1	Gene:	LamC / 36615	FlyBaseID:	FBgn0010397	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_003371.2	Gene:	VIM / 7431	HGNCID:	12692	Length:	466	Species:	Homo sapiens

Alignment Length:	472	Identity:	139/472 - (29%)
Similarity:	224/472 - (47%)	Gaps:	91/472 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VTLNTR-----------VSRASTSTPVGG--ASTSSRVGATSPTSPTR----------------- 40
            ||.:||           .||:..::..||  |:.||.|...|.....|
Human    31 VTTSTRTYSLGSALRPSTSRSLYASSPGGVYATRSSAVRLRSSVPGVRLLQDSVDFSLADAINTE 95

  Fly    41 --TSRQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAA 103
              .:|..||.|||.||||.|.|||::|.||.:|..|..||   :....:..|.|..:||:|:...
Human    96 FKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAEL---EQLKGQGKSRLGDLYEEEMREL 157

  Fly   104 RKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLA 168
            |:.:|:...:||::|:       |.|:|             ||:..||
Human   158 RRQVDQLTNDKARVEV-------ERDNL-------------AEDIMRL----------------- 185

  Fly   169 DRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTET 233
             |:|.:::    .|:.|.....|...|:.::..:|||:|||.:.:||:||:||..::|.:|:.|.
Human   186 -REKLQEE----MLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQEL 245

  Fly   234 RSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQ 298
            :::.|.:..:||..:|:   ..|..:|:::|.|||.....|.:|.|..|.::..:|..||||...
Human   246 QAQIQEQHVQIDVDVSK---PDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNND 307

  Fly   299 GSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRM 363
            ....|.:|....|.::..|..::..|:.||..|..::||:|.....|...:...|..|:.|:|.|
Human   308 ALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNM 372

  Fly   364 RDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPG------RPTTDSGISSNGSH 422
            ::|||..|:|||.|:::|::||:|||.|.|||.|||.|:::..|.      |.|....:....:|
Human   373 KEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLNLRETNLDSLPLVDTH 437

  Fly   423 -----LTASASSRSGRV 434
                 |..:..:|.|:|
Human   438 SKRTLLIKTVETRDGQV 454

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.