Protein Alignment LamC and lmna

DIOPT Version :9

• Sequence 1: NP_001260974.1
• Gene: LamC / 36615
• FlyBaseID: FBgn0010397
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001039148.1
• Gene: lmna / 733973
• XenbaseID: XB-GENE-920722
• Length: 668
• Species: Xenopus tropicalis
• Alignment Length: 595
• Identity: 214/595 - (35%)
• Similarity: 339/595 - (56%)
• Gaps: 51/595 - (8%)

  Fly    19 TPVGGASTSSRVGATSPTSPTRTSRQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQD 83
            ||  |...::| ...:|.||||.:|.||||:||.||||||.|||::|:||:||:.|...:..:::
 Frog     3 TP--GQKRATR-STHTPLSPTRITRLQEKEDLQELNDRLAVYIDKVRSLESENAGLRLRITESEE 64

  Fly    84 TVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENN 148
            .|:||.|.:|..||.|||.|||.||..|||:|:|::::.::.||:.:||.|..||..:...|:..
 Frog    65 VVSREVSGIKGAYEAELADARKTLDSVAKERARLQLELSKIREEHKELKARNAKKESDLLTAQAR 129

  Fly   149 ARLYENRYNEVNGKYNQSLADRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQ 213
            .:..|...|..:.....:|.:::..|::.:||.....:|...|.|.:|||:.|.|.|||.||:||
 Frog   130 LKDLEALLNSKDAALTTALGEKRNLENEIRELKAHIAKLEASLADTKKQLQDEMLRRVDTENRNQ 194

  Fly   214 SLREELAFKDQVHTQELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEI 278
            :|:|||.|:..:..:|:.||:.|.:..:.|:|....|::|:||..:||:||.|:|||:.:.:||:
 Frog   195 TLKEELEFQKNISNEEMRETKRRHETRMVEMDNGRQREFESKLADALQDLRAQHEGQVGLYKEEL 259

  Fly   279 ELLYDNEIQNLKAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLD 343
            |..|:.:::|.|.:|.|.:.....|.||::..|.:||.|:|:|..|:...|...|::|:||:...
 Frog   260 EKTYNAKLENAKQSAERNSSLVGEAQEEIQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDAYA 324

  Fly   344 TERQRHNQYIASLEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPG 408
            .||..:.:.::..:.|:..||..|..||.|||.|:|||::||:||.||.|||.|||.||.: ||.
 Frog   325 RERDSNRRLMSDKDREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRL-SPS 388

  Fly   409 RPTTD-----SGISSNGSHLTASASSRSGRVTPSGRRSATPGISGSSAVKRRRTVIDESEDRTLS 468
             |||.     :..|.:|:|:::|||.         ||....|.|||::
 Frog   389 -PTTQKRSARTVASHSGTHISSSASK---------RRRLEAGESGSTS----------------- 426

  Fly   469 EYSVNAAAKGDLEIIEADVEGRFIKLHNKGTEEINLTGWQLTRIAGDE-ELAFKFSRGSKVLGGA 532
             |:.:|...|.:.:.|.|.||::::|.||..|:.:|..||:.|..|:| .:.::|.....:..|.
 Frog   427 -YTQHARTTGKVSVEEVDPEGKYVRLRNKSNEDQSLGNWQIKRQIGEETPIVYRFPPRLTLKAGQ 490

  Fly   533 SVTIWSVDAGTAHDPPNNLVMK--KKWPVANSMRSVLANADKE-------VRVLSIYNTCG---- 584
            :||||:..||..::||.:||.|  ..|...:|:|:.|..::.|       ||.:.|.:..|
 Frog   491 TVTIWASGAGATNNPPTDLVWKAQSSWGTGDSIRTALLTSNNEEVAMRKLVRTVVINDEDGDDED 555

  Fly   585 TCDICRHCRH 594
            ..|:..|..|
 Frog   556 DDDVGHHHHH 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:278467	143/355 (40%)
		ATP-synt_B	<67..>142	CDD:304375	32/74 (43%)
		MreC	<178..>224	CDD:302802	22/45 (49%)
		LTD	473..574	CDD:279300	34/110 (31%)
lmna	NP_001039148.1	Filament	26..382	CDD:365827	143/355 (40%)
		LTD	431..538	CDD:395746	34/106 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	276	1.000	Domainoid score	I1707
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	391	1.000	Inparanoid score	I1944
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D204815at33208
OrthoFinder	1	1.000	-	-		FOG0001052
OrthoInspector	1	1.000	-	-		mtm9565
Panther	1	1.100	-	-	O	PTHR45721
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X632
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160