DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LamC and LOC683313

DIOPT Version :9

Sequence 1:	NP_001260974.1	Gene:	LamC / 36615	FlyBaseID:	FBgn0010397	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001094477.1	Gene:	LOC683313 / 683313	RGDID:	1588056	Length:	552	Species:	Rattus norvegicus

Alignment Length:	416	Identity:	114/416 - (27%)
Similarity:	200/416 - (48%)	Gaps:	68/416 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 RQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQD----TVNRETSNLKAVYEKELAAA 103
            |.:|:|:::.||::.|.:||::|.||.:|..|..:..|.|:    ||.:   .|:.::|:.:...
  Rat   149 RTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWALLQEQGTKTVRQ---GLETLFEQYINDL 210

  Fly   104 RKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRY-NEVNGKYNQSL 167
            ||.||....::.:|:.:::.:                :.||.:     |:::| :|:|
  Rat   211 RKELDNILGQRGRLDSELRNM----------------QGTVED-----YKSKYEDEIN------- 247

  Fly   168 ADRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTE 232
                      :..|.|||.:     .|:|.::|..:.:|:|:.:..||.:|:.|...::..||
  Rat   248 ----------RRTAAENEFV-----TLKKDVDAAYMNKVELQAKADSLTDEINFLRALYEAEL-- 295

  Fly   233 TRSRRQIEISEIDGRLS--RQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANR 295
              |:.|..||:....||  ......|...:.|::.|||...:.:|.|.|..|..:.:.|:..|.|
  Rat   296 --SQMQTHISDTSVVLSMDNNRSLDLDSIIAEVKAQYEEIAKRSRAEAESWYQTKYEELQITAGR 358

  Fly   296 AAQGSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAEL 360
            .........:|:..:...|..|.:::.:::...|.|.|.|.|.|...:...:.....:..||..|
  Rat   359 HGDDLRNTKQEISEINRMIQRLRSEIDHVKKQIANLQAAIAEAEQRGEMALKDARGKLEGLEDAL 423

  Fly   361 QRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTA 425
            |:.:.:||..|:|||.||::|::||:|||.|..||.|||.|||.|..| |...|.:.|     |.
  Rat   424 QKAKQDMARLLKEYQDLMNVKLALDVEIATYRTLLEGEECRLNGEGVG-PVNISVVQS-----TV 482

  Fly   426 SASSRSGRVTPSGRRSATPGISGSSA 451
            |:|..|     :|..|::.|:.|||:
  Rat   483 SSSYGS-----AGGASSSIGLGGSSS 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:278467	95/362 (26%)
		ATP-synt_B	<67..>142	CDD:304375	15/78 (19%)
		MreC	<178..>224	CDD:302802	13/45 (29%)
		LTD	473..574	CDD:279300
LOC683313	NP_001094477.1	Head	1..151		1/1 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		Keratin_2_head	15..148	CDD:292825
		Filament	151..464	CDD:278467	95/362 (26%)
		Coil 1A	152..187		12/34 (35%)
		Linker 1	188..206		5/20 (25%)
		Coil 1B	207..298		27/137 (20%)
		Linker 12	299..322		6/22 (27%)
		Coil 2	323..461		41/137 (30%)
		DUF883	377..>437	CDD:295076	15/59 (25%)
		Tail	462..552		19/53 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	524..552
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910