DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LamC and krt8.2

DIOPT Version :9

Sequence 1:	NP_001260974.1	Gene:	LamC / 36615	FlyBaseID:	FBgn0010397	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_031748531.1	Gene:	krt8.2 / 549551	XenbaseID:	XB-GENE-876686	Length:	408	Species:	Xenopus tropicalis

Alignment Length:	418	Identity:	100/418 - (23%)
Similarity:	205/418 - (49%)	Gaps:	75/418 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RRVTLNTRVSRASTSTPVGGASTSSRVGATSPTSPT----RTSRQQEKEELQHLNDRLACYIDRM 64
            :|.:.|..:||...|      |:|:.:.::.|....    :..|.||||:::.||::...:||::
Frog    40 QRSSSNLNLSRLPPS------SSSAFLLSSLPNMEVDPQMQQLRNQEKEQIKGLNNQFVNFIDKV 98

  Fly    65 RNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEEND 129
            |:||.:|..|..:|.|.::. :...||:..:.:......::.:|....||.||::::..:....:
Frog    99 RDLEKQNKILETQLALLKEK-DAYKSNIDQITQVSANRLKQQIDALLHEKEKLQMELHNMQGLVE 162

  Fly   130 DLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKFEDQAKELALENERL--RRQLD 192
            :||                     |||.:...:.||                :||:.:  ::.||
Frog   163 ELK---------------------NRYEDDINRRNQ----------------IENDFVLTKKDLD 190

  Fly   193 DLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIEISEIDGRLSRQYEAKLQ 257
            |       ..|.:||.|::..:|.:|:.:..|::.:||.|.  ..|::.:::...:....:.:::
Frog   191 D-------AYLHKVDNESKLDTLTDEIQYLKQLYDEELKEL--EHQVQNAKVTVAMDNSRDLEMK 246

  Fly   258 QSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALATEEVRLMRTKIDGLNAKLQ 322
            ..:.|::.||:...:.:::|.|..|:.:|::::....|       ..||::.::.:::.||..:|
Frog   247 HIMDEVKAQYQAMAQKSQQEAEYWYNCKIEDMENQVKR-------NNEELKALKNEVNDLNRMIQ 304

  Fly   323 NLEDTNAGLNARIRELENLLDTERQRHNQ--------YIASLEAELQRMRDEMAHQLQEYQGLMD 379
            .....|..|..:...||:.: :..:.|.:        :|..||..|:|.:.:||.:::|||.||:
Frog   305 RANSENEALKNQRANLESAI-SMAEEHGEDAVRNAKSHIRDLEEALKRAKQDMALKVREYQELMN 368

  Fly   380 IKVSLDLEIAAYDKLLCGEERRLNIESP 407
            ||::||:|||.|.|||.|||.|::.:.|
Frog   369 IKLALDIEIATYRKLLEGEETRMHGQKP 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:278467	89/365 (24%)
		ATP-synt_B	<67..>142	CDD:304375	15/74 (20%)
		MreC	<178..>224	CDD:302802	11/47 (23%)
		LTD	473..574	CDD:279300
krt8.2	XP_031748531.1	Filament	79..390	CDD:365827	89/365 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910