DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LamC and krt91

DIOPT Version :9

Sequence 1:	NP_001260974.1	Gene:	LamC / 36615	FlyBaseID:	FBgn0010397	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001003445.1	Gene:	krt91 / 445051	ZFINID:	ZDB-GENE-040801-181	Length:	466	Species:	Danio rerio

Alignment Length:	490	Identity:	125/490 - (25%)
Similarity:	203/490 - (41%)	Gaps:	123/490 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 TRVSRASTSTPV---------GGASTSSRVG-------ATSPTSPTRTSRQQEKEELQHLNDRLA 58
            ||:|.||.|...         |||......|       ..............:|..:|:||||||
Zfish    51 TRISSASASRSYSAGGGGGFGGGAGFGGGAGGGFGGGFGGGAGGDAFDVSANDKATMQNLNDRLA 115

  Fly    59 CYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKR 123
            .|::::|:||..|:.|  ||.:                       |:.||......|:   |...
Zfish   116 SYLEKVRSLEKANADL--ELKI-----------------------RQFLDSKTSPSAR---DYSA 152

  Fly   124 LWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKFEDQAKELALENERLR 188
            .:....||:.::...|:                  :||....|:.:.|...|..: :..|||...
Zfish   153 YYATISDLQNKIQDATR------------------INGGIYLSIDNAKLAADDFR-VKYENELSM 198

  Fly   189 RQ-----LDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIEISEIDGRL 248
            ||     :..|||.|:..|:.|.|||.|.:.|:|||.|..:.|.:||...|       .::.|::
Zfish   199 RQSVEADIAGLRKVLDELTMTRSDLEMQIEGLKEELIFLKKNHEEELLAAR-------GQMSGQV 256

  Fly   249 SRQYEAKLQQSL----QELRDQYEGQMRINREEIELLYDNEIQNLK---AAANRAAQGSALATEE 306
            ..:.:|..|:.|    .::|:.||.....|:.::|..:.::.::|.   ||:....|.:  .:|.
Zfish   257 HVEVDAAPQEDLTKVMADIREHYEQVAAKNQRDLEHWFQSKSESLNKEVAASTETLQST--KSEI 319

  Fly   307 VRLMRTKIDGLNAKLQ-------NLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMR 364
            ..|.|| :.||..:||       :||.|.|...||...:.|       .:...:.::|.:|.::|
Zfish   320 TELKRT-LQGLEIELQSQLSMKASLEGTLADTQARYGNMLN-------GYQMQVGNMEEQLMQLR 376

  Fly   365 DEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASS 429
            .::..|.||||.|:|||..|::|||.|.:||.||..|               ||.....|.::|:
Zfish   377 ADLERQGQEYQMLLDIKTRLEMEIAEYRRLLDGEASR---------------SSQTVSTTKTSST 426

  Fly   430 RSGRVTPSGRRSATPGISGSSAVKRRRTVIDESED 464
            .|         ||....|.|:..::..|:::|.:|
Zfish   427 SS---------SAPSSTSTSTTTRKVVTIVEEVKD 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:278467	102/374 (27%)
		ATP-synt_B	<67..>142	CDD:304375	14/74 (19%)
		MreC	<178..>224	CDD:302802	20/50 (40%)
		LTD	473..574	CDD:279300
krt91	NP_001003445.1	Filament	102..413	CDD:278467	102/374 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000