Protein Alignment LamC and KRT3

DIOPT Version :9

• Sequence 1: NP_001260974.1
• Gene: LamC / 36615
• FlyBaseID: FBgn0010397
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_024304743.1
• Gene: KRT3 / 3850
• HGNCID: 6440
• Length: 716
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 110/393 - (27%)
• Similarity: 190/393 - (48%)
• Gaps: 58/393 - (14%)

  Fly    43 RQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRE---TSNLKAVYEKELAAAR 104
            :.||:|:::.||::.|.:||::|.||.:|..|..:.||.|......   |:||:.::|..:...|
Human   283 KAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENHINYLR 347

  Fly   105 KLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLAD 169
            ..||....|:.:|:.::|.:.:..:|.|
Human   348 SYLDNILGERGRLDSELKNMEDLVEDFK------------------------------------- 375

  Fly   170 RKKFEDQA-KELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTET 233
             ||:||:. |..|.|||.:     .|:|.:::..:.:|:|:.:..:|.:|:.|...::..||
Human   376 -KKYEDEINKRTAAENEFV-----TLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAEL--- 431

  Fly   234 RSRRQIEISEIDGRLS--RQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRA 296
             |:.|..||:....||  ......|...:.|:|.|||...:.::.|.|.||..::..|:..|.|.
Human   432 -SQMQSHISDTSVVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRH 495

  Fly   297 AQGSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQ 361
            .........|:..:...|..|.|:::.::..||.|...|.|.|...:...:..|..:..|:|.||
Human   496 GDDLRNTKSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQ 560

  Fly   362 RMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTAS 426
            :.:|::|..|::||.||::|::||:|||.|.|||.|||.|::.|.|. ..:.|.:||:    |.|
Human   561 QAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPS-AVSISVVSSS----TTS 620

  Fly   427 ASS 429
            ||:
Human   621 ASA 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:278467	100/361 (28%)
		ATP-synt_B	<67..>142	CDD:304375	19/77 (25%)
		MreC	<178..>224	CDD:302802	12/45 (27%)
		LTD	473..574	CDD:279300
KRT3	XP_024304743.1	Keratin_2_head	<258..282	CDD:318448
		Filament	285..600	CDD:306535	100/361 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910