DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LamC and Iffo1

DIOPT Version :9

Sequence 1:	NP_001260974.1	Gene:	LamC / 36615	FlyBaseID:	FBgn0010397	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_006506337.2	Gene:	Iffo1 / 320678	MGIID:	2444516	Length:	563	Species:	Mus musculus

Alignment Length:	494	Identity:	96/494 - (19%)
Similarity:	173/494 - (35%)	Gaps:	165/494 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GASTSSRVGATSPTSPTRTSRQQEKEELQHLNDRLACYIDRMRNLENENSRLTQ----------- 76
            |...|||..|..|.| .|......:.....|....||:.....:.....|..|:
Mouse   138 GLPLSSRPAAVCPPS-ARVLGSPSRSPAGPLASSAACHTSSSTSTSTAFSSSTRFMPGTIWSFSH 201

  Fly    77 --------ELNLAQ----------------DTVNRETSNLKAVYEKELAAARKLLDETAKEKAKL 117
                    |..|.|                ||:   |..::|:| ..||..::..||
Mouse   202 ARRLGPGLEPTLVQGPGLSWVHPDGVGVQIDTI---TPEIRALY-NVLAKVKRERDE-------- 254

  Fly   118 EIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKFEDQAKELAL 182
               .||.|||...::.:|.::..|         |.|               :.::.:...:|||:
Mouse   255 ---YKRRWEEEYTVRIQLQERVTE---------LQE---------------EAQEADACQEELAM 292

  Fly   183 ENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVH-TQELTETRSRRQIE------ 240
            :.|:|:.:| .:.|.|.:..|..:|.:.|.::::.::....::. |.:|.:...:|..|
Mouse   293 KVEQLKAEL-VVFKGLMSNNLTELDTKIQEKAMKVDMDICRRIDITAKLCDLAQQRNCEDMIQMF 356

  Fly   241 ------------------------ISEIDGRLSRQYEA------------KLQQSLQELR----- 264
                                    :||.||  .||.|.            ::|:.|.:||
Mouse   357 QKKLVPSMGGRKRERKAAVEEDTSLSESDG--PRQPEGAEEESTALSINEEMQRMLSQLREYDFE 419

  Fly   265 DQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLEDTNA 329
            |..:.......||..||:::            ..|.|:|..|            |:.:..||:
Mouse   420 DDCDSLTWEETEETLLLWED------------FSGYAMAAAE------------AQGEQQEDS-- 458

  Fly   330 GLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKL 394
             |...|::.|:|..|..:.:.:.|..:|.||...:::|...|.||..:..:|..||:::....:|
Mouse   459 -LEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRL 522

  Fly   395 L--CGEER-----RLNIESPGRP-----TTDSGISSNGS 421
            :  .|:.:     .:.:..|..|     .:|..:||:.|
Mouse   523 ITQSGDRKSPAFTAVPLSDPPPPPSETEDSDRDVSSDSS 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:278467	82/445 (18%)
		ATP-synt_B	<67..>142	CDD:304375	20/109 (18%)
		MreC	<178..>224	CDD:302802	11/45 (24%)
		LTD	473..574	CDD:279300
Iffo1	XP_006506337.2	Filament	230..522	CDD:365827	72/360 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000