Protein Alignment LamC and lmnb2

DIOPT Version :10

• Sequence 1: NP_001260974.1
• Gene: LamC / 36615
• FlyBaseID: FBgn0010397
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_571077.2
• Gene: lmnb2 / 30196
• ZFINID: ZDB-GENE-990630-13
• Length: 583
• Species: Danio rerio
• Alignment Length: 576
• Identity: 213/576 - (36%)
• Similarity: 326/576 - (56%)
• Gaps: 59/576 - (10%)

  Fly    16 STSTPVGGASTSSRVGATSPTSPTRTSRQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNL 80
            :|:||      |....|.:|.||.|.||.||||||:.||||||.||||:|.||.||.||..:::.
Zfish     2 ATATP------SRASAAQTPLSPARISRLQEKEELRALNDRLAVYIDRVRALELENDRLQFKVSE 60

  Fly    81 AQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVA 145
            .::...||.|.:|::||.|||.||::|||||:|:|||:|::.::..|.:::.....||..:...|
Zfish    61 KEEVTTREVSGIKSLYEAELADARRVLDETARERAKLQIELGKVNSELEEVTRNYKKKDGDLAAA 125

  Fly   146 ENNARLYENRYNEVNGKYNQSLADRKKFEDQAKELALENERLRRQLDDL--------------RK 196
            ....:..|.:||:.....|.:|:              ||..|..:|.||              :|
Zfish   126 LVRIKDLEAQYNKNEAALNTALS--------------ENASLSAELADLKAQLAKAEDAHGVAKK 176

  Fly   197 QLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQ 261
            |||.|||.||||||:.|||.|||.|:..:..:|:.|||.|.:..:.|:|..:.:.||.||.|:||
Zfish   177 QLEVETLMRVDLENRCQSLTEELEFRKSMFDEEVRETRRRHEKRMVEVDSGMQQDYEFKLSQALQ 241

  Fly   262 ELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLED 326
            :||.|:|.|::|.:||::..:..::.|.|.:::...:....|.||::....:|:||:.:|..|:.
Zfish   242 DLRKQHEEQVQIYKEELQHTFKAKLDNAKVSSDLNDKAVLTAREELQEAHVRIEGLSYQLSALQK 306

  Fly   327 TNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAY 391
            ..:....||||||.||.::|.::.:.:.:.|.|:..||:.|..||.|||.|:|:|::||:||.||
Zfish   307 QASAAEERIRELEGLLSSDRDKYRRQLDAKEREMAEMRECMQQQLNEYQELLDVKLALDMEINAY 371

  Fly   392 DKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASSRSGRVTPSGRRSATPGISGSSAVKRRR 456
            .|||.|||.||.:.    |:..|.::.  |..|||::|.|.|               ||..||:|
Zfish   372 RKLLEGEEDRLKLS----PSPSSRVTV--SRTTASSTSASSR---------------SSRAKRKR 415

  Fly   457 TVIDESEDR-TLSEYSVNAAAKGDLEIIEADVEGRFIKLHNKGTEEINLTGWQLTRIAGD-EELA 519
            ..::||... ...:.|..|.|.|.:.|.|.|:||:.:.|.|...::.:|..|:|.|..|| ||:.
Zfish   416 VELEESSTAGPKVQISQQAEASGSVSIEEIDLEGKSVTLRNNSDKDQSLGSWRLKRQIGDGEEIV 480

  Fly   520 FKFSRGSKVLGGASVTIWSVDAGTAHDPPNNLVMKKK--WPVANSMRSVLANADKE 573
            :|||....:..|.:||:||.|||.:|.||::|:.|.:  |....::.::|.|:..|
Zfish   481 YKFSPKFVLKAGQTVTVWSADAGMSHSPPSDLLWKSQSSWGTGENILTLLVNSSGE 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:459643	145/369 (39%)
		PRK13922	154..>221	CDD:473155	29/80 (36%)
		LTD	474..574	CDD:460003	38/103 (37%)
lmnb2	NP_571077.2	Filament	25..381	CDD:459643	145/369 (39%)
		LTD	434..542	CDD:460003	38/103 (37%)