DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LamC and Prph

DIOPT Version :9

Sequence 1:	NP_001260974.1	Gene:	LamC / 36615	FlyBaseID:	FBgn0010397	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_006257383.1	Gene:	Prph / 24688	RGDID:	3414	Length:	506	Species:	Rattus norvegicus

Alignment Length:	450	Identity:	121/450 - (26%)
Similarity:	211/450 - (46%)	Gaps:	107/450 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SRASTSTPVGGASTSS----------RVGATSPTSPT-------------RTSRQQEKEELQHLN 54
            ||.|:|..:|..|.||          |.||....|..             ..:|..||:|||.||
  Rat    44 SRFSSSRLLGSGSPSSSARLGSFRAPRAGALRLPSERLDFSMAEALNQEFLATRSNEKQELQELN 108

  Fly    55 DRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEI 119
            ||.|.:|:::|.||.:|:.|..||:.|:   .:|.:....:.::||...|:.|:...:|:.::::
  Rat   109 DRFANFIEKVRFLEQQNAALRGELSQAR---GQEPARADQLCQQELRELRRELELLGRERDRVQV 170

  Fly   120 DIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKFEDQAKELALEN 184
            :...|.|:...||.||:::|::...||:|..|:
  Rat   171 ERDGLAEDLGALKQRLEEETRKREDAEHNLVLF-------------------------------- 203

  Fly   185 ERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETR---SRRQIEISEIDG 246
                      ||.::..||:|::||.:.:||.:|:.|..::|.:||.:.:   ..:|::..|::.
  Rat   204 ----------RKDVDDATLSRLELERKIESLMDEIEFLKKLHEEELRDLQVSVESQQVQQVEVEA 258

  Fly   247 RLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQ------------------------ 287
            .:    :.:|..:|:::|.|||.....|.:|.|..|.::::
  Rat   259 TV----KPELTAALRDIRAQYENIAAKNLQEAEEWYKSKVREQGRILGGVRGGGHWEWRRASQPG 319

  Fly   288 --------NLKAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDT 344
                    :|..||||..:....|.:|:...|.:|..|..::..|..||..|..::||||.....
  Rat   320 LSATEQYADLSDAANRNHEALRQAKQEMNESRRQIQSLTCEVDGLRGTNEALLRQLRELEEQFAL 384

  Fly   345 ERQRHNQYIASLEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNI 404
            |...:....|.||.||:::::|||..|:|||.|:::|::||:|||.|.|||.|||.|:::
  Rat   385 EAGGYQAGAARLEEELRQLKEEMARHLREYQELLNVKMALDIEIATYRKLLEGEESRISV 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:278467	107/390 (27%)
		ATP-synt_B	<67..>142	CDD:304375	20/74 (27%)
		MreC	<178..>224	CDD:302802	11/45 (24%)
		LTD	473..574	CDD:279300
Prph	XP_006257383.1	Filament_head	21..98	CDD:282575	12/53 (23%)
Prph	XP_006257383.1	Filament	99..441	CDD:278467	107/390 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910