DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LamC and ifd-1

DIOPT Version :9

Sequence 1:	NP_001260974.1	Gene:	LamC / 36615	FlyBaseID:	FBgn0010397	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_001024830.1	Gene:	ifd-1 / 187585	WormBaseID:	WBGene00002057	Length:	575	Species:	Caenorhabditis elegans

Alignment Length:	539	Identity:	138/539 - (25%)
Similarity:	233/539 - (43%)	Gaps:	80/539 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RVTLNTRVSR----ASTSTPVGGASTSSRVGATSPTSPT-RTSRQQEKEELQHLNDRLACYIDRM 64
            ||..|..:||    ..|:.|.|..|..|........:.| |.:|.:||.|:..||:|||.|::::
Worm     7 RVAHNPVLSRIIESGRTNLPSGITSAGSLSAYAQAAAVTIRDNRDREKREIADLNNRLARYVEKV 71

  Fly    65 RNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEEND 129
            |.||.:|..|..::.|.:...:..|..::..|:.|..:...|:.|...:.:..:.:|::
Worm    72 RFLEAQNRVLENDIGLFRQAAHIHTGKVRDYYDAEKTSLATLVREQEAKVSSAKQNIRK------ 130

  Fly   130 DLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKFEDQAKELA-LENE-----RLR 188
             |:|.:      .|.....|...|:|         |.:...||  :|.|.|: ||:|     ||.
Worm   131 -LEPEI------TTAIRTLASSLEHR---------QRVRSDKK--EQLKHLSDLESETAYIKRLI 177

  Fly   189 RQLDDLRKQLEAE----------TLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIEISE 243
            ...||.:..|:.|          .||..|.| :|...|.:.|.:|.:  ::|..|.|..:|.|.|
Worm   178 NDCDDEKSHLKTEISRIRGEIKRILALRDKE-RNGFSRSQTAAQDLL--KKLNATISTHEIAIRE 239

  Fly   244 IDGRLSRQ--------YEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGS 300
            ...:..|.        :..:|..|::|:|||:|...:..|:..|..|..:|..:|..:.:.:...
Worm   240 EINKARRDSTDKNREFFHRELHMSMKEIRDQFESDSKKARKTWEEWYKKKITEIKKRSEKFSLTQ 304

  Fly   301 ALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMRD 365
            ..|.|||..:|:.::.|..|:.:.:.....|:.||.:::...|.|.:...|.:...|..:.||||
Worm   305 NQAREEVLRIRSLLNELRTKISDADSMTQALSKRIEDMKFREDEELRMFEQSLTEKELAVTRMRD 369

  Fly   366 EMAHQLQEYQGLMDIKVSLDLEIAAYDKLL-CGEERRLNIESPGRPTTDSGISSNGSHLTASASS 429
            |.|....|.:.|::.:::|..|||.|.||: ..|..|.:.:|.....|.|.:....||...|:.|
Worm   370 ECAKLSVELETLVENQINLRSEIAHYRKLMEQAENLRTSYQSDFVIDTPSPLMRTSSHHYGSSYS 434

  Fly   430 RSGRVTPSGRRSATPGISGSSAVKRRRTV----IDESEDRTLSEYSVNAAAKGDLEIIEADVEGR 490
            .:.|.|                  ..:||    .|.|...|::.....:..|||::|||...|..
Worm   435 LNVRDT------------------HNKTVHHDNYDISSASTINTQQFRSYGKGDVKIIEHKDESI 481

  Fly   491 FIKLHNKGTEEINLTGWQL 509
            .|:..|....: :|:.|::
Worm   482 VIENSNSYKSK-DLSNWKI 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:278467	99/380 (26%)
		ATP-synt_B	<67..>142	CDD:304375	13/74 (18%)
		MreC	<178..>224	CDD:302802	18/61 (30%)
		LTD	473..574	CDD:279300	11/37 (30%)
ifd-1	NP_001024830.1	Filament	53..404	CDD:278467	98/377 (26%)
		MSP1_C	<167..348	CDD:284802	45/183 (25%)
		LTD	465..569	CDD:279300	11/36 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	196	1.000	Domainoid score	I1825
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H7818
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D204815at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920