Protein Alignment LamC and ifa-1

DIOPT Version :10

• Sequence 1: NP_001260974.1
• Gene: LamC / 36615
• FlyBaseID: FBgn0010397
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001360640.1
• Gene: ifa-1 / 181316
• WormBaseID: WBGene00002050
• Length: 604
• Species: Caenorhabditis elegans
• Alignment Length: 605
• Identity: 171/605 - (28%)
• Similarity: 308/605 - (50%)
• Gaps: 75/605 - (12%)

  Fly     7 TLNTRVSRASTSTPVGGASTSS--------------RVGATSPTSP--------TRTSRQQEKEE 49
            |::...:..|...|:||.:|.:              |.||.|..||        .|.||::||:|
 Worm    37 TMSFTSTTPSARAPLGGRTTGNVTSQDRMLKIVTEMRSGAGSGLSPFGQNAASTIRDSREREKKE 101

  Fly    50 LQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEK 114
            :..||||||.||:::|.||.:|.:|..:|:..:....::|.|::.:||.||..|:||:|||.|::
 Worm   102 MSDLNDRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNMYEGELVDAQKLIDETNKQR 166

  Fly   115 AKLEIDIKRLWEENDDLKPRLDKKTK--EATVAENNARL--YENRYNEVNGKYNQSLADRK--KF 173
            ..:|..:|::.:|..:::.:|:..||  |...|:.:|.|  ..|...|:      ||..|:  :.
 Worm   167 KDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDALLVTLSNLEAEI------SLLKRRIAQL 225

  Fly   174 EDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQ 238
            ||:.|.:..||:||..:|...|..|:.|||.|:|.:||.|:|.||:.|..:||..|:.|.::...
 Worm   226 EDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTLLEEIDFLRRVHDNEIKELQTLAS 290

  Fly   239 IEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALA 303
            .:.:..:...   ::.:|..:::::|::|:....::|.::|..|..::|.::..:.|.......|
 Worm   291 RDTTPENREF---FKNELSSAIRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYA 352

  Fly   304 TEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMA 368
            .|||:.:||::..|..||.:||..|:.|..:|:||...|:.:::.:...:...::::::||:|..
 Worm   353 KEEVKRLRTQLSDLRGKLADLESRNSLLEKQIQELNYQLEDDQRSYEAALNDRDSQIRKMREECQ 417

  Fly   369 HQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASSRSGR 433
            ..:.|.|.|:|.|.:||.|||.|.|:|.|||.|..:    :...:..:.::.  :|....:.:.|
 Worm   418 ALMVELQMLLDTKQTLDAEIAIYRKMLEGEENRAGL----KQLVEQVVKTHA--ITQETDTETMR 476

  Fly   434 VTPSGRRSATPGISGSSAVKRRRTVIDESEDRTLSEYSVNAAAKGDLEIIEADVEGRFIKLHNKG 498
            |           :.|.:|                |..|...:|||::.|.||..:|:||.|.|..
 Worm   477 V-----------VKGETA----------------SRQSFQRSAKGNVSIHEASPDGKFIVLQNTH 514

  Fly   499 TEEINLTG-WQL-TRIAGDEELAFKFSRGSKVLGGASVTIWSVDAGTAHDPPNNLV--MKKKWPV 559
            ..:....| |:| .||.|..|..:...|...:..|.::.|::.:.|.| .||:.||  .:..:..
 Worm   515 RAKDEAIGEWKLKRRIDGKRENVYTLPRDFVLRAGKTLKIFARNQGVA-SPPDQLVYDAEDSFGS 578

  Fly   560 ANSMRSVLANADKEVRVLSI 579
            .|:::::|.|.:.|.|...|
 Worm   579 GNNVQTILFNKEGEERATHI 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:459643	115/361 (32%)
		PRK13922	154..>221	CDD:473155	26/68 (38%)
		LTD	474..574	CDD:460003	30/103 (29%)
ifa-1	NP_001360640.1	Filament	98..450	CDD:459643	115/360 (32%)
		LTD	491..597	CDD:460003	32/106 (30%)