DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LamC and ifp-1

DIOPT Version :9

Sequence 1:	NP_001260974.1	Gene:	LamC / 36615	FlyBaseID:	FBgn0010397	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_509628.1	Gene:	ifp-1 / 181182	WormBaseID:	WBGene00002067	Length:	776	Species:	Caenorhabditis elegans

Alignment Length:	455	Identity:	98/455 - (21%)
Similarity:	189/455 - (41%)	Gaps:	80/455 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 SRQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKL 106
            ::..|:::|..|||:....|:.:..:|.|::.|..:.||.:..|..::|.:..:|..|:...|..
Worm    16 AKLSERQDLVQLNDQFVDIIEHVHYMEAEHTALEHDYNLLKSGVQSDSSGINEIYNVEIRTVRSG 80

  Fly   107 LDETAK-------EKAKLEIDIK---RLW-----------EENDDLKPRLDKKTKEATVAENNAR 150
            ::|..:       |:.:|...:|   :||           :|.||...|:.....|..:.:...:
Worm    81 IEEINRSRHELLNEQTQLSHQVKEAEQLWRHTAKSALGVPKEVDDEFHRICHIKMEDCITKRRIK 145

  Fly   151 LYENRYNEV---NGKYNQSLADRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQN 212
            ..|::...:   ||:..:.:...:..:|||  ::|:.|.|      |||.....::..::.:|:.
Worm   146 YMEDKLRLIKQNNGRIFEHINLMRMRKDQA--VSLQQEYL------LRKNELLHSIRNMEEDNKK 202

  Fly   213 QSLREELAFKDQVHTQELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREE 277
            ..:.|        |...:.:..:.|.:            :..:|::::.::|..||.....|.||
Worm   203 IIMNE--------HKYFVRDRNADRHV------------FRDQLRKAIADIRADYEANRLRNEEE 247

  Fly   278 IELLYDNEIQNLKAAANRAAQGSAL---ATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELE 339
            |.:..:.||..:    |....|...   ..||:.:::..:.||..::..:|..|..|..:| |..
Worm   248 IRIRLEREIHRM----NTTMPGVVCYDKLREELSIVKNNLSGLQKQVSEVEIRNNSLTQQI-EFY 307

  Fly   340 NLLDTERQRHNQYIASLE---AELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERR 401
            .|..:|..:  .:..:||   .|:::||::......|.:.|.|:.:.|..|||.|.:||
Worm   308 RLEISENNK--LFEDTLEFKIKEIEKMREQCTAISVELEKLCDLNIDLQKEIAKYRELL------ 364

  Fly   402 LNIESPGRPTTDSGISSNGSHLTASASSRSGRVTPSGRRSATPGISGSSAVKRRRTVIDESEDRT 466
               :..|.|..    ::..:.:.|||.||....:.|...|.|.  ||.........|.|.|..||
Worm   365 ---DRSGDPRA----NAPSTQVIASALSRQNYSSISDHHSRTS--SGIVQHTAHHAVRDSSSSRT 420

Fly 467 466
Worm 421 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:278467	81/385 (21%)
		ATP-synt_B	<67..>142	CDD:304375	20/95 (21%)
		MreC	<178..>224	CDD:302802	8/45 (18%)
		LTD	473..574	CDD:279300
ifp-1	NP_509628.1	Filament	19..365	CDD:278467	81/389 (21%)
ifp-1	NP_509628.1	LTD	662..>734	CDD:303230
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0977
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H7818
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810