Protein Alignment LamC and ifa-4

DIOPT Version :10

• Sequence 1: NP_001260974.1
• Gene: LamC / 36615
• FlyBaseID: FBgn0010397
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_508836.5
• Gene: ifa-4 / 180765
• WormBaseID: WBGene00002052
• Length: 575
• Species: Caenorhabditis elegans
• Alignment Length: 587
• Identity: 168/587 - (28%)
• Similarity: 286/587 - (48%)
• Gaps: 68/587 - (11%)

  Fly     7 TLNTRVSRASTSTPVGGASTSSRVGATSP-----TSPTRTSRQQEKEELQHLNDRLACYIDRMRN 66
            |:::..||....|.:||::.:|   ..||     .|..|.||.:||:|:..||||||.||:::|.
 Worm    29 TISSGTSRTLKITEIGGSNLTS---GMSPFGGHAASAIRESRTREKKEMSELNDRLASYIEKVRF 90

  Fly    67 LENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEENDDL 131
            ||.:|.::.::|||.:.....:::::|.:||.||.:|:.|:.::.||:|:||..||:|.||.::.
 Worm    91 LEAQNRKMEKDLNLLRGKWGHDSTSVKVMYETELRSAKDLIADSDKERAQLEDQIKKLVEELNNY 155

  Fly   132 KPRLDKKTKEATVAENNARLYENRYNEVNGKYNQ-----SLADRK--KFEDQAKELALENERLRR 189
            :.:|.:       ||..|.:.....:.|.|:...     .|..|:  ..|:....|..||.|:..
 Worm   156 RNKLHE-------AERGADVTRKELDNVLGRLGALEAEIELLKRRISLMEESIGHLKRENHRMID 213

  Fly   190 QLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTE--TRSRRQIEISEIDGRLSRQY 252
            .|...|..:|.|||.|:|.:||.|:|.||..|..::|..|:.:  ..:.|...:.      :|:|
 Worm   214 SLHHARNAVEQETLNRIDYQNQVQTLLEECDFIRRIHDSEIHDLLAMASRDTTVE------NREY 272

  Fly   253 -EAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALATEEVRLMRTKIDG 316
             :.:|..:::|:|.:|:......|.:||..|..::|.:....:|.......|.|||:.:||.:..
 Worm   273 FKNELSSAIREIRSEYDHVSNTTRTDIESWYKLKVQEIHTQNSRNCLEQNYAREEVKRLRTTLGD 337

  Fly   317 LNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQEYQGLMDIK 381
            :..|:.:||..|..|..:|.:|...::.:.:.:.|.:...:..:.::|||....:.|.|.|:|.|
 Worm   338 MRGKMADLEGRNLLLEKQIEDLNYQMEEDMRSYEQSLNDKDTSINKLRDESKILMVELQMLIDTK 402

  Fly   382 VSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASSRSGRVTPSGRRSATPGI 446
            .:||.||..|.|:|.|||.|..:    |...:..:.:...|.|....|.  ||.
 Worm   403 QTLDAEIVIYRKMLDGEENRAGL----RQLVEQVVKTTSIHQTKEIESL--RVL----------- 450

  Fly   447 SGSSAVKRRRTVIDESEDRTLSEYSVNAAAKGDLEIIEADVEGRFIKLHNKGTEEINLTGWQLTR 511
                            :..|.|..|.:.:|||::.|.||:..|::|.|.|....:.|:..|:|.|
 Worm   451 ----------------KGETTSHSSYSRSAKGNIAIQEAEPSGKYIVLENISRRDENIGDWKLRR 499

  Fly   512 -IAGDEELAFKFSRGSKVLGGASVTIWSVDAGTAHDPPNNLV--MKKKWPVANSMRSVLANADKE 573
             |||..|:.|.|.|...:....||.|::...| .|.||::||  ::..:...|.:.:.|.|.:.|
 Worm   500 KIAGKREIVFTFPREFTLRAQKSVKIFARGQG-VHSPPDSLVYDLEDSFGTGNDVVTTLYNKEGE 563

  Fly   574 VR 575
            .|
 Worm   564 DR 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:459643	110/365 (30%)
		PRK13922	154..>221	CDD:473155	23/73 (32%)
		LTD	474..574	CDD:460003	33/102 (32%)
ifa-4	NP_508836.5	Filament	70..422	CDD:459643	110/364 (30%)
		LTD	463..570	CDD:460003	35/104 (34%)