Protein Alignment LamC and ifc-2

DIOPT Version :10

• Sequence 1: NP_001260974.1
• Gene: LamC / 36615
• FlyBaseID: FBgn0010397
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001362085.1
• Gene: ifc-2 / 180414
• WormBaseID: WBGene00002056
• Length: 1339
• Species: Caenorhabditis elegans
• Alignment Length: 617
• Identity: 151/617 - (24%)
• Similarity: 261/617 - (42%)
• Gaps: 135/617 - (21%)

  Fly     4 RRVTLNTRVSRA-------STSTPVGG----ASTSSRVGATSPTSPTRTSRQQEKEELQHLNDRL 57
            ||| |.:.:||.       ::.|...|    .|..|..||.. |:..|.:|::||.|:..|||||
 Worm   717 RRV-LGSGMSRTYSEGRGLASGTYASGFGQLVSGMSSAGAIC-TTQIRDAREREKREIGLLNDRL 779

  Fly    58 ACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDI- 121
            |.||:::|.||.:|..|:.::::.::..: ...::..:::.|:..|:.:|::|...::..|.||
 Worm   780 ADYIEKVRFLEAQNRCLSHDIDILRNGFS-GGGHVSGLFDAEINQAKHILEQTTAHRSTFERDIT 843

  Fly   122 ---------KRLW-----------EENDDLKPRLDKKTKEATVAENNARLYENRY----NEVNGK 162
                     ::.|           |::|....||.|...|.::.:...|:.|...    .|.:|.
 Worm   844 GLSAEIEVFRKKWLDAVNAVKAHREDHDVDLDRLAKIEAEISLFKRKIRIVEEDVIRIRRENDGI 908

  Fly   163 YNQSLADRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDL---ENQNQSLREELAFKDQ 224
            ||: :|..|:...  .|:||:||| ...:.||        |.|::|   || |..:.:||.|
 Worm   909 YNE-IARIKQLTH--NEIALKNER-SLNVSDL--------LQRINLLQTEN-NVRIEQELVF--- 957

  Fly   225 VHTQELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNL 289
                      .||.......|     .:..:||.:::::|..||.....||::||:.|..:|:.:
 Worm   958 ----------IRRDTTADNRD-----YFRHELQAAIRDIRADYEAISIRNRQDIEVWYREQIRKI 1007

  Fly   290 KAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIA 354
            :..:.|.  ...|..||:..:||.:..:.::|..:|..|..|...|.:|:|  :.|.:.....:|
 Worm  1008 QDESVRV--NPDLYKEELISIRTTVTNVRSRLAEVEGRNFFLERLIDDLKN--NEEAKFFEISLA 1068

  Fly   355 SLEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEE---RRLNIESPG-------- 408
            ..:|::..:||:......:.:.|.|.::||..||..|..||.|..   ...|....|
 Worm  1069 ERDAQIATLRDQCTELSIQMEKLCDNEISLRAEIERYRILLNGANVTTYTSNTHGSGSGIAVGGV 1133

  Fly   409 --------RPTTDSGISSNGSHLTASAS----SRSGRV----------TPSGRRSATPGISGSSA 451
                    ..||.:..|||.|:....||    |.||.|          :......||.||.||..
 Worm  1134 VGGSTRVISQTTRTHSSSNTSYSNVPASRGGYSISGNVGGISVGGTIGSHGASAHATGGIIGSGV 1198

  Fly   452 VKRRRTV----IDESEDRTLSEYSVNAAAK-------GDLEIIEADVEGRFIKLHN-KGTEEINL 504
            ...|.:|    .|:..||...|..|:.:.:       |.:.|.:  |...:|:|.| .....:::
 Worm  1199 QAHRGSVSSLITDKPRDRVHDEKGVDQSGRHFHSWYLGTISINQ--VTPSYIELKNICKIRRVDV 1261

  Fly   505 TGWQLTRIAGDEELAFKFSRGSKVLGGASVTI 536
            .|:::.:           |...:|||.|.:.:
 Worm  1262 GGFRIEQ-----------SVNGQVLGSAQINV 1282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:459643	97/386 (25%)
		PRK13922	154..>221	CDD:473155	22/73 (30%)
		LTD	474..574	CDD:460003	12/71 (17%)
ifc-2	NP_001362085.1	Filament	768..1111	CDD:459643	96/378 (25%)