DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LamC and ifc-1

DIOPT Version :9

Sequence 1:	NP_001260974.1	Gene:	LamC / 36615	FlyBaseID:	FBgn0010397	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	NP_503783.1	Gene:	ifc-1 / 178747	WormBaseID:	WBGene00002055	Length:	500	Species:	Caenorhabditis elegans

Alignment Length:	448	Identity:	101/448 - (22%)
Similarity:	190/448 - (42%)	Gaps:	80/448 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 GGASTSSRVGATSP----TSPTRTSRQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQ 82
            ||..|:...|.:|.    |:..|.:|::||.|:..||||||.||:::|.|:.:|..|:.::.:
Worm     5 GGIPTNLVSGMSSAGAICTTQIRDAREREKREIGLLNDRLADYIEKVRFLKAQNHVLSHDIEI-- 67

  Fly    83 DTVNRETS---NLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATV 144
              :.|..|   ::.:.:|.|::....:.:.....:.|.:.||                     |.
Worm    68 --LRRGFSGGGHISSFFESEISNCTVISERILSSRTKFQADI---------------------TG 109

  Fly   145 AENNARLYENRYNE----VNGKYNQSLADRKKFEDQAKELALENERLRRQLDD-LRKQLEAETLA 204
            .|....:|..::.|    |.........:..|..:...::||.|.::|...:| ||.:.|...:.
Worm   110 LEGEIEIYRKKWLEALKVVRSHREDHHVNLDKLAEVEAQIALFNRKIRIVEEDVLRIRRETGGIQ 174

  Fly   205 RVDLENQNQSLREELAFKDQVH--TQEL--------TETRSRRQIEISEI--DGRLSRQ--YEAK 255
            . |:...:..:..|:|.|::.|  .|.|        ||..||.:.|:..|  |..|..:  :..:
Worm   175 N-DIGRIHSQIHAEIALKNERHHSVQMLLQRVQVIQTENSSRIEQELIYIHRDTTLENRDYFRQE 238

  Fly   256 LQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALATEEVRLMRTKIDGLNAK 320
            ||.:::::|..||.....:||:||:.|...|..::...  |........||:..:||.:...:::
Worm   239 LQAAMRDIRANYEAMSIRSREDIEIAYRKRIDEIRVIP--AHVHIEDYREELLSIRTTLSTTHSR 301

  Fly   321 LQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQEYQGLMDIKVSLD 385
            |..:|..||.|...|.:|::....|.:.....:.:.:|..::.::.......:.:.|.|.:.||.
Worm   302 LAEIESRNAWLLTTITDLKHQQAEEARIFEATLDAKQATYEQFKERCTELSIQMEKLCDHETSLQ 366

  Fly   386 LEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASSRSGRVTPSGRRSAT 443
            .|:..|..||                       ||:::|...|:.:|   .:|.||:|
Worm   367 AELERYRVLL-----------------------NGANVTTYVSNSTG---AAGYRSST 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:278467	84/377 (22%)
		ATP-synt_B	<67..>142	CDD:304375	10/77 (13%)
		MreC	<178..>224	CDD:302802	12/46 (26%)
		LTD	473..574	CDD:279300
ifc-1	NP_503783.1	Filament	33..378	CDD:278467	84/395 (21%)
		DUF1517	382..>484	CDD:295038	7/20 (35%)
		Loricrin	<386..487	CDD:292475	6/16 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0977
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H7818
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D204815at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820