Protein Alignment LamC and lmn-1

DIOPT Version :9

• Sequence 1: NP_001260974.1
• Gene: LamC / 36615
• FlyBaseID: FBgn0010397
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_492371.1
• Gene: lmn-1 / 172687
• WormBaseID: WBGene00003052
• Length: 566
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 185/595 - (31%)
• Similarity: 301/595 - (50%)
• Gaps: 80/595 - (13%)

  Fly     1 MSARRVTLNTRVSRASTSTPVGGASTSSRVGATSPTSPT--RTSRQQEKEELQHLNDRLACYIDR 63
            ||:|:   .||.||..|......:|.|:..|.......|  .|||.|||:.|..||.|||.|||:
 Worm     1 MSSRK---GTRSSRIVTLERSANSSLSNNGGGDDSFGSTLLETSRLQEKDHLTSLNSRLATYIDK 62

  Fly    64 MRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWEEN 128
            :|.||.||:||..::...:....:|.|||...:|.|.|..|:.||....|.||..|:......|.
 Worm    63 VRQLEQENNRLQVQIRDIEVVEKKEKSNLADRFEAEKARLRRALDSAQDELAKYRIEYDAAKVEV 127

  Fly   129 DDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKFEDQAKE---------LALEN 184
            ..|||:::|..:|...||..|            .:.||:||    :.|||:         |.:||
 Worm   128 KKLKPQVEKLERELAGAEEQA------------LHAQSIAD----QSQAKQKTLQARNDKLVVEN 176

  Fly   185 ERLRRQ-------LDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIEIS 242
            :.|::|       ::.|:|.:|.|||.|....|:.::|.|:|||..|.|..||.|.|.:||::::
 Worm   177 DDLKKQNITLRDTVEGLKKAVEDETLLRTAANNKIKALEEDLAFALQQHKGELEEVRHKRQVDMT 241

  Fly   243 EIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALATEEV 307
            ....:::.:|::|||..::|:|.|::..:..|:...|..|.|:   |.||..|..:..:.|..
 Worm   242 TYAKQINDEYQSKLQDQIEEMRAQFKNNLHQNKTAFEDAYKNK---LNAARERQEEAVSEAIH-- 301

  Fly   308 RLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQ 372
                     |.|::::||.:::|..:.|..|.:.|||.::...:.:...:|.:..:..|:...:.
 Worm   302 ---------LRARVRDLETSSSGNASLIERLRSELDTLKRSFQEKLDDKDARIAELNQEIERMMS 357

  Fly   373 EYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASSRSGRVTPS 437
            |:..|:|:|:.||.|:..|..||.|||.|||:      |.::..:::..|::.|:.
 Worm   358 EFHDLLDVKIQLDAELKTYQALLEGEEERLNL------TQEAPQNTSVHHVSFSSG--------- 407

  Fly   438 GRRSATPGISGSSAVKRRRTVIDESEDRTLSEY-----SVNAAAKGDLEIIEADVEGRFIKLHNK 497
                   |.|....|||||.|....||:.: :|     .:|....|.:.|.|.|.||:::::.|.
 Worm   408 -------GASAQRGVKRRRVVDVNGEDQDI-DYLNRRSKLNKETVGPVGIDEVDEEGKWVRVANN 464

  Fly   498 GTEEINLTGWQLTRIAGDEELAFKFSRGSKVLGGASVTIWSVDAGTAHDPPNNLVMKK-KWPVAN 561
            ..||.::.|::|...||::|.:|:||...|:...||.|:||.|||..|.||...|||| :||:.:
 Worm   465 SEEEQSIGGYKLVVKAGNKEASFQFSSRMKLAPHASATVWSADAGAVHHPPEVYVMKKQQWPIGD 529

  Fly   562 SMRSVLANAD 571
            :..:.|.:::
 Worm   530 NPSARLEDSE 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:278467	116/371 (31%)
		ATP-synt_B	<67..>142	CDD:304375	25/74 (34%)
		MreC	<178..>224	CDD:302802	19/61 (31%)
		LTD	473..574	CDD:279300	37/100 (37%)
lmn-1	NP_492371.1	Filament	44..386	CDD:278467	116/371 (31%)
		DUF2317	<57..147	CDD:302887	33/89 (37%)
		LTD	443..547	CDD:279300	36/97 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167841
Domainoid	1	1.000	83	1.000	Domainoid score	I5342
eggNOG	1	0.900	-	-		E1_KOG0977
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I1864
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48052
OrthoDB	1	1.010	-	-		D204815at33208
OrthoFinder	1	1.000	-	-		FOG0001052
OrthoInspector	1	1.000	-	-		otm14477
orthoMCL	1	0.900	-	-		OOG6_103212
Panther	1	1.100	-	-	O	PTHR45721
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2618
SonicParanoid	1	1.000	-	-		X632
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.840