Protein Alignment LamC and Gfap

DIOPT Version :10

• Sequence 1: NP_001260974.1
• Gene: LamC / 36615
• FlyBaseID: FBgn0010397
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_030101431.1
• Gene: Gfap / 14580
• MGIID: 95697
• Length: 470
• Species: Mus musculus
• Alignment Length: 522
• Identity: 151/522 - (28%)
• Similarity: 231/522 - (44%)
• Gaps: 101/522 - (19%)

  Fly     1 MSARRVTLNTRVSRASTSTPVGGASTSSRVGA--------TSPTSPTRT--------------SR 43
            |..||:| :.|.|.|| .|.|.|...|.::|.        .:|..|.|.              :|
Mouse     1 MERRRIT-SARRSYAS-ETVVRGLGPSRQLGTMPRFSLSRMTPPLPARVDFSLAGALNAGFKETR 63

  Fly    44 QQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLD 108
            ..|:.|:..||||.|.||:::|.||.:|..|..|||..:   .:|.:.|..||:.||...|..||
Mouse    64 ASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLR---AKEPTKLADVYQAELRELRLRLD 125

  Fly   109 ETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKF 173
            :.....|:||::.....::...|:.:|..:|.....||||...|
Mouse   126 QLTANSARLEVERDNFAQDLGTLRQKLQDETNLRLEAENNLAAY--------------------- 169

  Fly   174 EDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETR---S 235
                                 |::.:..||||||||.:.:||.||:.|..:::.:|:.|.|   :
Mouse   170 ---------------------RQEADEATLARVDLERKVESLEEEIQFLRKIYEEEVRELREQLA 213

  Fly   236 RRQIEISEIDGRLSRQYEAK--LQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQ 298
            ::|:.: |:|       .||  |..:|:|:|.|||.....|.:|.|..|.::..:|..||:|.|:
Mouse   214 QQQVHV-EMD-------VAKPDLTAALREIRTQYEAVATSNMQETEEWYRSKFADLTDAASRNAE 270

  Fly   299 GSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRM 363
            ....|..|....|.::..|...|::|..||..|..::||.|.....|...:.:.:|.||.|.|.:
Mouse   271 LLRQAKHEANDYRRQLQALTCDLESLRGTNESLERQMREQEERHARESASYQEALARLEEEGQSL 335

  Fly   364 RDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRL--------NIESPGRPTTDSGISSNG 420
            ::|||..|||||.|:::|::||:|||.|.|||.|||.|:        |::..|..:|..|   .|
Mouse   336 KEEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRGGKSTKEG---EG 397

  Fly   421 SHLTASASSRSGRVTPSGRRSATPGISGSSAVKRRRTVIDE---SEDRTLSEYSVNAAAKGDLEI 482
            ..:|......:.:|.|........|     |:....|.:|.   ||........|......|.|:
Mouse   398 QKVTRPLKRLTIQVVPIQAHQIENG-----ALPAAETSLDTKSVSEGHLKRNIVVKTVEMRDGEV 457

  Fly   483 IE 484
            |:
Mouse   458 IK 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:459643	115/360 (32%)
		PRK13922	154..>221	CDD:473155	13/66 (20%)
		LTD	474..574	CDD:460003	3/11 (27%)
Gfap	XP_030101431.1	Filament_head	4..63	CDD:461414	15/60 (25%)
		Filament	65..373	CDD:459643	115/360 (32%)