DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LamC and krt78.1

DIOPT Version :9

Sequence 1:	NP_001260974.1	Gene:	LamC / 36615	FlyBaseID:	FBgn0010397	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_002935786.2	Gene:	krt78.1 / 100491159	XenbaseID:	XB-GENE-6035591	Length:	493	Species:	Xenopus tropicalis

Alignment Length:	431	Identity:	105/431 - (24%)
Similarity:	208/431 - (48%)	Gaps:	67/431 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 RQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNL--AQDTVNRETSNLKAVYEKELAAARK 105
            |::|:|:::.||::.|.:||::|.||.:|..|..:.:|  .|......:|.:::::...:.:.|.
Frog   119 RKEEREKIKLLNNKFASFIDKVRFLEQQNKVLETKWSLLQKQQVSKSRSSEIESIFNTLITSLRS 183

  Fly   106 LLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADR 170
            .||...|:|..|..:::.:.:..::.|.:.:.:.|:.|..||:
Frog   184 QLDSLVKDKGLLGGELQVMKDHAENFKNKFELEFKKRTADEND---------------------- 226

  Fly   171 KKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRS 235
                                ...|:|.::|..|.:|.||.:.::|.:||||...::.:||...:.
Frog   227 --------------------FVSLKKDVDATYLIQVQLETKQKALDDELAFLRNLYKEELDGIKQ 271

  Fly   236 R---RQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAA 297
            :   ..:.:|..:.|:     ..|...:.:::.|||...|.::||.|..|.::.|.|:.||.:..
Frog   272 QTAGTSVVLSMDNSRM-----LDLGDIIADVKAQYEDTTRRSKEEAEAAYQSKYQQLQLAAGQQG 331

  Fly   298 QGSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQR 362
            :....:.:|:..:...:..|..::::::...|.|...|::.|...|...:...:.:.:||..||:
Frog   332 EDLKSSKKEISEVNRSVQKLRNEIESVKKQIASLQVSIQDSERRGDIALRDAQEKLVNLERALQK 396

  Fly   363 MRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGIS-SNGSHLTAS 426
            .:.|||.||:|||.|:::|::||:|||.|.|||.|||.|:.    |:.:....:| .:|:..:..
Frog   397 AKQEMAQQLREYQTLLNVKLALDVEIATYRKLLEGEESRIT----GQVSDAVTVSFVSGAKSSFD 457

  Fly   427 ASSRSGRVTPSGRRSATPGISGSSAVKRRRTVIDESEDRTL 467
            |:.||..:....:|      .|||.||    :|.::|..:|
Frog   458 ATKRSAGIDTGVKR------RGSSGVK----IISKTESSSL 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:278467	88/360 (24%)
		ATP-synt_B	<67..>142	CDD:304375	15/76 (20%)
		MreC	<178..>224	CDD:302802	12/45 (27%)
		LTD	473..574	CDD:279300
krt78.1	XP_002935786.2	Keratin_2_head	<94..118	CDD:374433
krt78.1	XP_002935786.2	Filament	121..435	CDD:365827	88/360 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D204815at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920