DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LamC and krt98

DIOPT Version :9

Sequence 1:	NP_001260974.1	Gene:	LamC / 36615	FlyBaseID:	FBgn0010397	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_005155788.1	Gene:	krt98 / 100124615	ZFINID:	ZDB-GENE-070822-8	Length:	391	Species:	Danio rerio

Alignment Length:	414	Identity:	108/414 - (26%)
Similarity:	194/414 - (46%)	Gaps:	90/414 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SRASTSTPVGGA-STSSRVGATSPTSPTRTSRQ------------QEKEELQHLNDRLACYIDRM 64
            |.:.|.:..||| ...:|:  :||.....:|.:            .:|..:|:||.|||.|::::
Zfish     5 SNSKTLSVYGGAGGRGTRI--SSPAGFLNSSPRGFNLVDGLDLSADKKATMQNLNTRLASYLEKV 67

  Fly    65 RNLENENSRLTQELN---LAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEIDIKRLWE 126
            |:||..|:.|.|:::   .:.|.|..:.:|    ::..:...|...:..:::.|||.:::.....
Zfish    68 RSLEKANTELEQKISDWYDSHDDVTFDHTN----FQDTIQDLRNEFNTRSQDNAKLILEVDNAKL 128

  Fly   127 ENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKFEDQAKELALENERLRRQL 191
            ..||.|                 |.|||                        |||:..| :....
Zfish   129 AADDFK-----------------RKYEN------------------------ELAMRRE-IEADT 151

  Fly   192 DDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTET-RSRRQIEISEIDGRLSRQYEAK 255
            .:|||.|:..:|:|.|||.|.::|:||.....:.|.:.:|.| .:..|:.:| :|...|..
Zfish   152 GNLRKILDEFSLSRSDLELQIEALKEEFIVLKKNHKENITLTIETGGQVNVS-VDAAPSMD---- 211

  Fly   256 LQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALATEEVRLMRTKIDGLNAK 320
            |.|::.|:|..||...:.||||:|..|::::..::       |..:...||::..||::..|.:.
Zfish   212 LNQAIDEIRQHYETVTQKNREELESWYESKMAPMQ-------QEVSNHNEELQDSRTELKDLTST 269

  Fly   321 LQNLE---DTNAGLNARI-RELENLLDTERQRHNQY------IASLEAELQRMRDEMAHQLQEYQ 375
            ||.|:   .|:..:.:.: .:||   |||.:..||.      :::||.:|.:....:|:..:||:
Zfish   270 LQRLQIELQTHQSMKSNLDGQLE---DTEARYGNQLAGLQTTVSNLEDQLSQFHANIANNKEEYE 331

  Fly   376 GLMDIKVSLDLEIAAYDKLLCGEE 399
            .|:|:|..|:.|||.|.:||.||:
Zfish   332 TLLDVKTRLEREIAEYRRLLDGEK 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:278467	99/369 (27%)
		ATP-synt_B	<67..>142	CDD:304375	15/77 (19%)
		MreC	<178..>224	CDD:302802	17/45 (38%)
		LTD	473..574	CDD:279300
krt98	XP_005155788.1	Filament	50..356	CDD:278467	99/367 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000