DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LamC and ina

DIOPT Version :9

Sequence 1:	NP_001260974.1	Gene:	LamC / 36615	FlyBaseID:	FBgn0010397	Length:	640	Species:	Drosophila melanogaster
Sequence 2:	XP_004915909.1	Gene:	ina / 100101732	XenbaseID:	XB-GENE-492716	Length:	491	Species:	Xenopus tropicalis

Alignment Length:	512	Identity:	149/512 - (29%)
Similarity:	239/512 - (46%)	Gaps:	111/512 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RASTSTPVGGASTSSRVGATS------------PTSP-------------------TRTS----- 42
            |||::..  |.|:|||..|||            |::|                   |:||
Frog    22 RASSARL--GVSSSSRATATSGYRSHSLSRSNVPSAPSYRRASRGAGYLAGDNLDLTQTSAVNNE 84

  Fly    43 ----RQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAA 103
                |..|||:||.||||.|.:|:::.|||.:|..|..||...:.. ..|.|.|..:|::|:...
Frog    85 YKIIRTNEKEQLQGLNDRFAMFIEKVHNLEQQNKVLETELTALRQR-QSEPSRLGELYQQEIKEL 148

  Fly   104 RKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLA 168
            |..|:|...|||::.|       |.|:|:..|.|                     :.|||...:.
Frog   149 RAQLEELNAEKAQIII-------ERDNLEDDLQK---------------------LKGKYEDEIR 185

  Fly   169 DRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTET 233
            .|::     .|.||::.         :|.::..||||:|||.:.:||.:|::|..:||.:|:||.
Frog   186 MREE-----TEYALKSH---------KKDVDDATLARLDLEKKVESLLDEISFLRKVHDEEVTEL 236

  Fly   234 RSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQ 298
            .:..|.....::..||:   ..|..:|:|:|.|||.....|.:..:..|.::..||...|:|:.:
Frog   237 MAMLQASQVSVEMELSK---PDLTSALKEIRSQYESLAAKNLQSADEWYKSKFANLTEQASRSTE 298

  Fly   299 GSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRM 363
            ......||:...|.::.....::::|..||..|..:::|:|:....|.......|..||.||:..
Frog   299 LIRANREEINDYRRQLQSKTIEIESLRGTNESLERQLQEMEDRHMAETAGLQDTINQLENELRNT 363

  Fly   364 RDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGIS---------SN 419
            :.|||..|:|||.|:::|::||:|||||.|||.|||.|.         :.:|||         .:
Frog   364 KGEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRF---------STAGISMMPFNPNPPPS 419

  Fly   420 GSHLTASASSRSGRVTP---SGRRSATPGISGSSAVKRRRTVIDESEDRTLSEYSVN 473
            .|:.:...||.:.:|||   |.::..|.|:  |..|.:..|.|.|:.:..:.|..|:
Frog   420 YSYQSRVHSSSTSKVTPAVDSRKKEETDGV--SKVVSKSSTRIGETYEEIIEETVVS 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:278467	112/355 (32%)
		ATP-synt_B	<67..>142	CDD:304375	23/74 (31%)
		MreC	<178..>224	CDD:302802	15/45 (33%)
		LTD	473..574	CDD:279300	0/1 (0%)
ina	XP_004915909.1	Filament_head	8..90	CDD:368088	16/69 (23%)
ina	XP_004915909.1	Filament	91..401	CDD:365827	112/355 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910