DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ttv and extl2

DIOPT Version :9

Sequence 1:	NP_001356963.1	Gene:	ttv / 36614	FlyBaseID:	FBgn0265974	Length:	772	Species:	Drosophila melanogaster
Sequence 2:	NP_001070029.1	Gene:	extl2 / 558373	ZFINID:	ZDB-GENE-060929-1122	Length:	332	Species:	Danio rerio

Alignment Length:	317	Identity:	80/317 - (25%)
Similarity:	140/317 - (44%)	Gaps:	66/317 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   443 NSSPGALLTLPTFADSSRYMPFLLNSMGAEPRHNYTAVIYVQIGAALGPNAALYKLVRTITKSQF 507
            |.....|..|...:::||.:        |:|..::|.::     ........|.:|:........
Zfish    40 NEDINILRELRRSSNTSRTL--------ADPEESFTIIM-----QTYNRTDVLLRLLNHYQAVPH 91

  Fly   508 VERILVLWAADRPLPLKKRWPPTSHIPLHVISLGGSTRSQGAGPTSQTTEGRPSISQRFLPYDEI 572
            ::.|:::|......|.::.|......|:.|:     .|.|...          .:..|.:.:.::
Zfish    92 LQCIIIVWNNPGETPPRRLWDELGPHPVPVL-----FREQRVN----------RMRNRLMMHPDV 141

  Fly   573 QTDAVLSLDEDAILNTDELDFAYTVWRDFPERIVGYPARAHFWDDSKNAWGYTS--------KWT 629
            :|||||.||:|.:|:..::.||::||:.||::|||:..|.|. ..:...:.|.|        ...
Zfish   142 KTDAVLMLDDDILLSVPDISFAFSVWKQFPDQIVGFVPRKHV-SSASGVYSYGSFELQDPDKGGG 205

  Fly   630 NYYSIVLTGAAFYHRYYNYLYTNWLSLLLLKTVQQ-----------SSNCEDILMNLLVSHVTRK 683
            :.||::|.||:|:||.:            ||..|:           :.||:||.||.:|:....|
Zfish   206 DRYSMILVGASFFHRRF------------LKQFQEQPAEVHTLLDRTQNCDDIAMNFIVARQLSK 258

  Fly   684 PPIKVTQRKGY-----KDRETG-RSPWNDPDHFIQRQSCLNTFAAVFGYMPLIRSNL 734
            .|..|..:..:     ||..:| ...|:.|:|.:||..|||..|.::|:|||..||:
Zfish   259 RPSGVFVKPVHMSNLEKDASSGFVGMWHRPEHMLQRSYCLNKLAQIYGHMPLRYSNI 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttv	NP_001356963.1	Exostosin	102..393	CDD:335188
ttv	NP_001356963.1	Glyco_transf_64	477..737	CDD:337333	73/283 (26%)
extl2	NP_001070029.1	Glyco_transf_64	66..314	CDD:286358	71/280 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D314330at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920