Protein Alignment ttv and extl3

DIOPT Version :10

• Sequence 1: NP_001356963.1
• Gene: ttv / 36614
• FlyBaseID: FBgn0265974
• Length: 772
• Species: Drosophila melanogaster
• Sequence 2: NP_001008036.1
• Gene: extl3 / 493398
• XenbaseID: XB-GENE-855819
• Length: 919
• Species: Xenopus tropicalis
• Alignment Length: 845
• Identity: 225/845 - (26%)
• Similarity: 367/845 - (43%)
• Gaps: 203/845 - (24%)

  Fly    40 ESAKDGGVQPHEQLPSFLGAHDMQELQLLQSNQSK-SL---------DSSKHLVTRKPDCRMETC 94
            |:||    |...||.:.:...:....:|:..||.| ||         |.:..|...|.:|.:..|
 Frog   122 ENAK----QDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDINIPLPKSKRNCGLHNC 182

  Fly    95 FDFTRC--YDRFLVYIYPP---------EPLNSLGAAPPTSANYQKILTAIQESRYYTSDPTAAC 148
            ||::||  ...|.|::|..         :||..           |.:..:::.:.|.|.:...||
 Frog   183 FDYSRCPLTSGFPVFVYNSDQYPFGNFIDPLIK-----------QALEASVRNNVYVTENANNAC 236

  Fly   149 LFVLGIDTLDRDSLSEDYVRNVPSRLARLPYW-NNGRNHIIFNLYSGTWPDYAENSL-GFDAGEA 211
            ::|:.:..:....:.:.  ..:..:|..|||| .:|.||:|.||   :.....:|.| ....|.|
 Frog   237 IYVVLMGEMQEPVMPKP--TELEEQLHSLPYWRTDGHNHLIINL---SRKSETQNYLYNVSTGRA 296

  Fly   212 ILAKASMGVLQLRHGFDVSI-PLFHKQFPLRAGATGTVQSNNF-------PANKKYLLAFKGKRY 268
            ::|:::...||.|.|||:.: ||.|           .:...||       |..:|||.:|:|::.
 Frog   297 MIAQSTFYDLQYRPGFDIVVSPLVH-----------AMSEPNFLEIPPQVPVKRKYLFSFQGEKI 350

  Fly   269 VHGIGSETRNSLFHLHNGRDMV-----------LVTTCRHGKSWRELQDNRCDEDNREY------ 316
                 ...|:||....:..:.:           ::||.      :.:||::.|....|:
 Frog   351 -----ESLRSSLQEARSFEEEMEGNAPADYDDRIITTL------KAVQDSKLDFVMVEFTCKNQA 404

  Fly   317 ------------DRYDYETLLQNSTFCLV--PRGRRL-----GSFRFLEALQAGCIPVLLSNAWV 362
                        :|.|...||:.|||.|:  |...:|     .:.|..|||:.|.|||:|.....
 Frog   405 KPSLPTEWALCGERDDRLELLKQSTFALIITPGDSQLVISAGSAMRLFEALEVGAIPVILGEQVQ 469

  Fly   363 LPFESKIDWKQAAIWADERLLLQVPDIVRSIPAERIFALRQQTQVLWERYFGSIEKIVFTTFEII 427
            ||:...|.|.:|.:...:..:.:|..::|||....:.:||:|.:.|||.||.:.:.:..|....:
 Frog   470 LPYHDTIRWNEAVLILPKPRITEVHFLLRSISDNDLLSLRRQGRFLWETYFSTSDTVFNTILATV 534

  Fly   428 RER--LPDYPVRSSLV------------------------------------------------- 441
            |.|  :|..|::....
 Frog   535 RTRIQIPAAPIKEEPAVEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPKYLRNFTLTAAD 599

  Fly   442 ----WNSSPGALLTLPTFADSSRYMP----FLLNSMGAEPRHNYTAVIYVQIGAALGPNA----- 493
                ||::||.....| .......:|    ||.:..|..|..........:..||||.|.
 Frog   600 IYRNWNTAPGPFHLFP-HTPFDPLLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVPREQF 663

  Fly   494 -----------ALYKLVRTITKSQFVERILVLWAADRPLPLKKRWPPTSHIPLHVISLGGSTRSQ 547
                       .|...:..:....::.:::|:|.:.: ||.:....|...:|:.::
 Frog   664 TVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPK-LPSEDLLWPDIGVPIVIV--------- 718

  Fly   548 GAGPTSQTTEGRPSISQRFLPYDEIQTDAVLSLDEDAILNTDELDFAYTVWRDFPERIVGYPARA 612
                   .|| :.|::.||||:|:|:|:||||:|:||.|..||:.|.:.|||:..:||||:|.|.
 Frog   719 -------RTE-KNSLNNRFLPWDQIETEAVLSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRY 775

  Fly   613 HFWDDSKNAWGYTSKWTNYYSIVLTGAAFYHRYYNYLYTNWLSLLLLKTVQQSSNCEDILMNLLV 677
            |.||....:|.|.|.::...|:|||||||:|:||.|||:..:...:...|.:..|||||.||.||
 Frog   776 HAWDIPHRSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLV 840

  Fly   678 SHVTRKPPIKVTQRKGYKDRETGRSPWNDPDHFIQRQSCLNTFAAVFGYMPLIRSNLRMDPMLYR 742
            ||:|||||||||.|..::.....::..:|..||.:|..|:|.|..|:|||||:.:..|:|.:|::
 Frog   841 SHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFK 905

  Fly   743  742
             Frog   906  905

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ttv	NP_001356963.1	Exostosin	102..393	CDD:397245	79/345 (23%)
		Glyco_transf_64	477..737	CDD:430488	98/275 (36%)
extl3	NP_001008036.1	TPR_MLP1_2	<71..150	CDD:462316	7/31 (23%)
		Exostosin	190..500	CDD:397245	79/347 (23%)
		Glyco_transf_64	663..900	CDD:430488	93/254 (37%)