Protein Alignment ttv and botv

DIOPT Version :10

• Sequence 1: NP_001356963.1
• Gene: ttv / 36614
• FlyBaseID: FBgn0265974
• Length: 772
• Species: Drosophila melanogaster
• Sequence 2: XP_321405.4
• Gene: botv / 1281488
• VectorBaseID: AGAMI1_001299
• Length: 957
• Species: Anopheles gambiae
• Alignment Length: 883
• Identity: 262/883 - (29%)
• Similarity: 397/883 - (44%)
• Gaps: 227/883 - (25%)

  Fly    26 RLKVSPLRPRRAQHESAKDGGVQPHEQLPSFLGAHDMQELQLLQSNQSKSLDSSKHLVTRKPDCR 90
            |||:|..:.:.||.|:....  .|...||..|.:..:..       |.:.:|::     ....|:
Mosquito   140 RLKISVEQAQVAQREAVLRN--TPELALPRALFSDTLPA-------QMRPIDAA-----HSRSCK 190

  Fly    91 METCFDFTRC--YDRFLVYIYPPEPLNSLGAAPPTSANYQ---KILTAIQESRYY----TSDPTA 146
            |.||||.:||  ...|.||:|.|:..:.:      ||.|.   .:.|.|:::..|    |:||..
Mosquito   191 MSTCFDHSRCSLTSGFPVYLYDPDTTSVV------SAGYDIDGFLKTTIKQTLGYNAHLTTDPKK 249

  Fly   147 ACLFVLGIDTLDRDSLSEDYVR-----------------------NVPSRLARLPYW-NNGRNHI 187
            ||:|::    |..::|||..|:                       || :||..|||| .:||||:
Mosquito   250 ACVFLV----LVGEALSEHEVQKSNRYVAPQGAADGSGAPNLSSLNV-TRLRLLPYWGGDGRNHV 309

  Fly   188 IFNLYSGTWPDYAENSLG-----------FDAGEAILAKASMGVLQLRHGFDVSIPLFHKQFPLR 241
            :.|        :|...:|           .|.|.|:|.::|....|.|.|||:..|      |:.
Mosquito   310 LLN--------FARREVGPGAGNMLQGQAMDTGRAMLVQSSFEESQFRVGFDLIAP------PIL 360

  Fly   242 AGATGTVQSN---NFPANKKYLLAFKGK-----------RYVHGIGSETRNS-----LFHLHNGR 287
            ....|.|...   ..||.:||||:|:|:           |......|:|.:.     |..:.:||
Mosquito   361 GPPGGDVWQECAPMLPARRKYLLSFQGELLGQNGSMVGPRGTDDTESDTVDEFIIEHLKEMSSGR 425

  Fly   288 D---MVLVTTCRHGKSWRE---LQD-NRCDEDNREYDRYDYETLLQNSTFCLV--PRGRRLGS-- 341
            .   .:|...|......|.   |:| :.|..||..      :::|:.|||.|:  |.|....|
Mosquito   426 TQDYFMLQFECVPATEQRAPSGLRDWSLCGTDNSR------KSVLKESTFALLLAPGGGSTSSTL 484

  Fly   342 --FRFLEALQAGCIPVLLSNAWV-LPFESKIDWKQAAIWADERLLLQVPDIVRSIPAERIFALRQ 403
              .|..|||:||.||::|....| ||:...|||::..|...:..:.::..::|:||...:..:|:
Mosquito   485 LQARLYEALRAGAIPLVLGGDQVQLPYAETIDWRRVVISLPKARITELHFLLRAIPDADLLTMRR 549

  Fly   404 QTQVLWERYFGSIEKIVFTTFEIIRERL--PDYPVRSSL---VWNSSPGALLTLPTFADSSRYMP 463
            |.:::||||..|::..|.|....:|.||  |..|:.|.:   |:|||...|.:.|.......
Mosquito   550 QGRLVWERYLSSVQSTVDTIVASLRSRLGIPPKPIPSVIAHSVFNSSFVPLKSDPVIDTEPE--- 611

  Fly   464 FLLNSMG-AEP-------RHNYTA----------------VIYVQI------------------- 485
               .|:| .||       |.||||                .:|.|:
Mosquito   612 ---ESLGPIEPPYPSPAFRRNYTATLVQSREMWNDWADPFALYPQLPFDPVLPSDAKFIGSHMGF 673

  Fly   486 --------------GAALG---PNAALYKLVRTITKSQ-------------FVERILVLWAADRP 520
                          |.:||   |......::.|..:.|             ::.:::|:|.:.:|
Mosquito   674 RPIGKGAGGTGKEFGESLGGNYPREQFTIVILTYEREQVLMDSLSRLYGLPYLHKVIVVWNSPKP 738

  Fly   521 LPLKK-RWPPTSHIPLHVISLGGSTRSQGAGPTSQTTEGRPSISQRFLPYDEIQTDAVLSLDEDA 584
             ||:. |||... :|:||:          ..|       |.|::.||||:|.|:|:||||:|:||
Mosquito   739 -PLEDLRWPDIG-VPVHVV----------RAP-------RNSLNNRFLPFDAIETEAVLSVDDDA 784

  Fly   585 ILNTDELDFAYTVWRDFPERIVGYPARAHFWD-DSKNAWGYTSKWTNYYSIVLTGAAFYHRYYNY 648
            .|..||:.|.:.|||:..:|:||:|.|.|.|| :|.::|.|.|.::...|:|||||||.|:||.|
Mosquito   785 HLRHDEILFGFRVWREHRDRVVGFPGRFHAWDVNSLDSWNYNSNYSCELSMVLTGAAFIHKYYTY 849

  Fly   649 LYTNWLSLLLLKTVQQSSNCEDILMNLLVSHVTRKPPIKVTQRKGYKDRETGRSPWNDPDHFIQR 713
            |||..|...:...|.:..|||||.||.||||||||||:|||.|..::......|...|..||.:|
Mosquito   850 LYTYTLPQAIRDKVDEYMNCEDIAMNFLVSHVTRKPPVKVTSRWTFRCPGCPVSLSEDDTHFQER 914

  Fly   714 QSCLNTFAAVFGYMPLIRSNLRMDPMLYRDPVSNLRKK 751
            ..|:|.|..||||.||:.:..|.|.:|::..:.:.::|
Mosquito   915 HKCINFFTKVFGYTPLLNTQYRADSILFKTRIPHDKQK 952

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ttv	NP_001356963.1	Exostosin	102..393	CDD:397245	98/365 (27%)
		Glyco_transf_64	477..737	CDD:430488	111/326 (34%)
botv	XP_321405.4	COG4372	<66..>182	CDD:443500	12/50 (24%)
		Exostosin	202..539	CDD:397245	98/367 (27%)
		Glyco_transf_64	700..938	CDD:430488	102/256 (40%)