DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ttv and LOC108179064

DIOPT Version :9

Sequence 1:	NP_001356963.1	Gene:	ttv / 36614	FlyBaseID:	FBgn0265974	Length:	772	Species:	Drosophila melanogaster
Sequence 2:	XP_021323864.1	Gene:	LOC108179064 / 108179064	-ID:	-	Length:	313	Species:	Danio rerio

Alignment Length:	338	Identity:	163/338 - (48%)
Similarity:	211/338 - (62%)	Gaps:	45/338 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAKKRYILV-FVSCAFLAYAYFGGYRLKVSPLRPRRAQHESAKDGGVQP--------HEQLPSF 56
            |||:|:|:|: ..:|.::...|:.|.:.::..|...|.        |..|        ...||:|
Zfish     1 MQARKKYVLLGLCTCCWILLYYWAGLQERLLGLITHRR--------GEVPRPWPDWLDRALLPNF 57

  Fly    57 LGAHDMQELQLLQSN---------QSKSLDSSKHLVTRKPDCRMETCFDFTRCYDR--FLVYIYP 110
            ....|:|       |         |.|...||.:..:|   |||:|||||.||..:  |.|||||
Zfish    58 AEQLDLQ-------NGGGPGDSPRQRKQAWSSIYKDSR---CRMDTCFDFGRCQTQSGFRVYIYP 112

  Fly   111 PEPLNSLGAAPPTSANYQKILTAIQESRYYTSDPTAACLFVLGIDTLDRDSLSEDYVRNVPSRLA 175
            ||      .....|.:|:||||::.|||||||||..||||||||||||||.||:.:|.||..|:.
Zfish   113 PE------KGERVSESYRKILTSVSESRYYTSDPREACLFVLGIDTLDRDQLSQQFVPNVDERIR 171

  Fly   176 RLPYWNNGRNHIIFNLYSGTWPDYAENSLGFDAGEAILAKASMGVLQLRHGFDVSIPLFHKQFPL 240
            ..|.||:||||:||||||||||:|.|: |||:.|:|||||||:.....|.|||:|||||.|:.|.
Zfish   172 GYPLWNDGRNHVIFNLYSGTWPNYTED-LGFNVGQAILAKASLNTEHFRPGFDISIPLFSKEHPQ 235

  Fly   241 RAGATGTVQSNNFPANKKYLLAFKGKRYVHGIGSETRNSLFHLHNGRDMVLVTTCRHGKSWRELQ 305
            :.|..|.:..|:.|..:||||.||||||:.||||:|||:|.|:|||:|:|.:|||||||.|.:.:
Zfish   236 KGGKRGWLVRNSVPPRRKYLLMFKGKRYLTGIGSDTRNALHHIHNGKDIVSLTTCRHGKDWEKHK 300

  Fly   306 DNRCDEDNREYDR 318
            |.|||.||:||:|
Zfish   301 DARCDHDNQEYER 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttv	NP_001356963.1	Exostosin	102..393	CDD:335188	129/219 (59%)
ttv	NP_001356963.1	Glyco_transf_64	477..737	CDD:337333
LOC108179064	XP_021323864.1	Exostosin	103..>311	CDD:308581	126/214 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581961
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D314330at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940