DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ttv and LOC101885478

DIOPT Version :9

Sequence 1:	NP_001356963.1	Gene:	ttv / 36614	FlyBaseID:	FBgn0265974	Length:	772	Species:	Drosophila melanogaster
Sequence 2:	XP_017208153.1	Gene:	LOC101885478 / 101885478	-ID:	-	Length:	745	Species:	Danio rerio

Alignment Length:	783	Identity:	407/783 - (51%)
Similarity:	517/783 - (66%)	Gaps:	67/783 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAKKRYILVFVSCAFLAYAYFGGYRLKVSPLRPRRAQHESAKDGGVQPHEQLPSF--------- 56
            |||||||:||.|....|..||..|.::         .:..|.....:....|:|||
Zfish     1 MQAKKRYLLVSVGACSLLLAYLCGLQI---------GEFHSQNRAALYGLSQVPSFPPRWPEWVD 56

  Fly    57 ------LGAHDMQE---LQLLQSNQSKSLDSSKHLVTRKPDCRMETCFDFTRCYDRFLVYIYPPE 112
                  ||..:.:|   |.|.|....:.....:..:.:...|||:|||||.||...|.:|:|||:
Zfish    57 PPLQTYLGEAEQEEDGPLLLHQHTSPRERREIQKNIYKSRRCRMDTCFDFQRCERGFKIYVYPPQ 121

  Fly   113 PLNSLGAAPPTSANYQKILTAIQESRYYTSDPTAACLFVLGIDTLDRDSLSEDYVRNVPSRLARL 177
            .    |..|  |.:|||||.||:|||:||:||..||||||.|||||||.||..||.||.:|:..|
Zfish   122 K----GEVP--SESYQKILAAIEESRFYTTDPNEACLFVLSIDTLDRDQLSAQYVHNVRARIQSL 180

  Fly   178 PYWNNGRNHIIFNLYSGTWPDYAENSLGFDAGEAILAKASMGVLQLRHGFDVSIPLFHKQFPLRA 242
            |.|..||||:||||||||||||.| .||||.|:|:|||||..:...|..||:|||||.|..|.:.
Zfish   181 PLWYEGRNHLIFNLYSGTWPDYTE-ELGFDIGQAMLAKASTDMDNFRPHFDISIPLFSKDHPQKG 244

  Fly   243 GATGTVQSNNFPANKKYLLAFKGKRYVHGIGSETRNSLFHLHNGRDMVLVTTCRHGKSWRELQDN 307
            |..|.:..||.|..:||||.||||||:.||||||||:|:|:|||.|::|:|||:|||.|.:.:|.
Zfish   245 GDKGFLNLNNVPPLRKYLLVFKGKRYLTGIGSETRNALYHIHNGDDIILLTTCKHGKDWEKHKDA 309

  Fly   308 RCDEDNREYDRYDYETLLQNSTFCLVPRGRRLGSFRFLEALQAGCIPVLLSNAWVLPFESKIDWK 372
            |||.||.||.::||:.||.||:|||||||||||||||||||||.||||||||.|.|||...|||.
Zfish   310 RCDRDNEEYTKFDYQELLHNSSFCLVPRGRRLGSFRFLEALQAACIPVLLSNGWELPFSEVIDWS 374

  Fly   373 QAAIWADERLLLQVPDIVRSIPAERIFALRQQTQVLWERYFGSIEKIVFTTFEIIRERLPDYPVR 437
            :|||..|||||||||.|.||:.::||.|||||||.||:.||.|:.|||.||.||:.:|:..:..|
Zfish   375 KAAIIGDERLLLQVPSITRSVGSDRILALRQQTQFLWDAYFSSVTKIVLTTLEIVHDRIRTHMSR 439

  Fly   438 SSLVWNSSPGALLTLPTFADSSRYMPFLLNSMGAEPRHNYTAVIYVQIGAALGP----NAALYKL 498
            |..:|||.||.|..||.|:......||..:::|..|...:||:|     .||.|    ...::||
Zfish   440 SRQMWNSLPGGLYALPEFSSDLSLFPFYYSTLGKSPPQEFTAII-----QALTPLQSQQQPIFKL 499

  Fly   499 VRTITKSQFVERILVLWAADRPLPLKKRWPPTSHIPLHVISLGGSTRSQGAGPTSQTTEG-RPSI 562
            :..:.||:|..:|||||..::|.|.:.:||..: .|..:|                  || |.::
Zfish   500 IHAVAKSKFCVQILVLWNCEKPPPPRNKWPSIT-TPFSII------------------EGKRKTM 545

  Fly   563 SQRFLPYDEIQTDAVLSLDEDAILNTDELDFAYTVWRDFPERIVGYPARAHFWDDSKNAWGYTSK 627
            |.||.|:..|:||||||||||::|:|:|:|||:.||:.||:||||||||:|:||..|..||||||
Zfish   546 SGRFYPHQAIKTDAVLSLDEDSVLSTNEVDFAFIVWQSFPDRIVGYPARSHYWDSGKGRWGYTSK 610

  Fly   628 WTNYYSIVLTGAAFYHRYYNYLYTNWLSLLLLKTVQQSSNCEDILMNLLVSHVTRKPPIKVTQRK 692
            |||.||:||||||||||||::|||::|.:.||..|.|.:||||||:|.|:|.||:.|||||||:|
Zfish   611 WTNEYSMVLTGAAFYHRYYHHLYTHYLPMSLLSMVDQLANCEDILINFLISAVTKLPPIKVTQKK 675

  Fly   693 GYKD----RETGRSPWNDPDHFIQRQSCLNTFAAVFGYMPLIRSNLRMDPMLYRDPVSNLRKKYR 753
            .||:    :.:..|.|.|||||.|||||:|:|.:.||:|||:.|.||:||:|::|.||.||||||
Zfish   676 QYKETMMQQGSKASRWADPDHFAQRQSCMNSFTSWFGFMPLLHSQLRLDPVLFKDQVSILRKKYR 740

  Fly   754 QIE 756
            .||
Zfish   741 DIE 743

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ttv	NP_001356963.1	Exostosin	102..393	CDD:335188	184/290 (63%)
ttv	NP_001356963.1	Glyco_transf_64	477..737	CDD:337333	136/268 (51%)
LOC101885478	XP_017208153.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D314330at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010