Protein Alignment ttv and ext2

DIOPT Version :10

• Sequence 1: NP_001356963.1
• Gene: ttv / 36614
• FlyBaseID: FBgn0265974
• Length: 772
• Species: Drosophila melanogaster
• Sequence 2: NP_001120887.1
• Gene: ext2 / 100151709
• XenbaseID: XB-GENE-867542
• Length: 718
• Species: Xenopus tropicalis
• Alignment Length: 712
• Identity: 248/712 - (34%)
• Similarity: 366/712 - (51%)
• Gaps: 119/712 - (16%)

  Fly    89 CRMETCFDFTRC----YDRFLVYIYP-----PEPLNSLGAAPPTSANYQKILTAIQESRYYTSDP 144
            |||.||||..||    .::..|||||     .|...|:|..  .|..|.::|:|:.:|.:||.|.
 Frog    85 CRMHTCFDVYRCGFNPKNKVKVYIYPLKKYTDEYDGSVGGT--ISREYNQLLSAVSQSDFYTEDV 147

  Fly   145 TAACLFVLGIDTLDRDSLSEDYVRNVPSRLARLPYWNNGRNHIIFNLYSGTWPDYAENSLGFDAG 209
            :.||||:..||.|:::||.   ::.....||:||.|:.|.||::||:..|..||| ..:|.....
 Frog   148 SRACLFLPSIDVLNQNSLR---IKETAQALAQLPRWDRGSNHLLFNMLPGGPPDY-NTALDVPRD 208

  Fly   210 EAILAKASMGVLQLRHGFDVSIPLFHK-----QFPLRAGATGTVQSNNFPANKKYLLAFKGKRYV 269
            .|:||.........|.|:|||||::..     ..|.:|           |..:.:.| ...:..:
 Frog   209 RALLAGGGFSTWTYRQGYDVSIPVYSSLSAEVNLPEKA-----------PGPRAHFL-LSSQTSL 261

  Fly   270 HGIGSETRNSL--FHLHNGRDMVLVTTCRHGKSWRELQDNRCDEDNREYDR--YDYETLLQNSTF 330
            |   .|.|:.|  ....||..::::..|.:..........||      |..  |||..:||.|||
 Frog   262 H---PEFRSELEAIRAENGESVLILEKCSNYTDGAAAHRKRC------YRNVVYDYPQILQESTF 317

  Fly   331 CLVPRGRRLGSFRFLEALQAGCIPVLLSNAWVLPFESKIDWKQAAIWADERLLLQVPDIVRSIPA 395
            |:|.||.|||.....:.|||||:||::::::||||...:|||:|::...|..:.::..|::::|.
 Frog   318 CIVLRGARLGQSVLSDVLQAGCVPVIIADSYVLPFSEVLDWKRASVVIPEEKMFEMYSILQAVPQ 382

  Fly   396 ERIFALRQQTQVLWERYFGSIEKIVFTTFEIIRERLPDYPVRSSLVWNSSPGAL-------LTLP 453
            .::..:::|.:..||.||.|::.|...|.:||.:|:..|..||...||..|...       |.||
 Frog   383 RQLEEMQRQARWFWEGYFSSMKSIALATLQIINDRIYPYAARSYEEWNGPPAVQWSSVNNPLFLP 447

  Fly   454 TFADSSRYMPFLLNSMGAEPRHNYTAVI--YVQIGAALGPNAALYKLVRTITKSQFVERILVLWA 516
            .....|:               .:|||:  |.::       .:|::::..::|...:.::||:|.
 Frog   448 LIPPQSQ---------------GFTAVVLTYDRV-------ESLFRVITEVSKVPSLSKLLVVWN 490

  Fly   517 ADRPLPLKKRWPPTSHIPLHVISLGGSTRSQGAGPTSQTTEGRPSISQRFLPYDEIQTDAVLSLD 581
            .....|.:....|...:||.|:               :|||.:  :|.||.||.||:|:|||::|
 Frog   491 NQNKNPPEVSVWPKIRVPLKVV---------------KTTENK--LSNRFFPYSEIETEAVLAID 538

  Fly   582 EDAI-LNTDELDFAYTVWRDFPERIVGYPARAHFWDDSKNAWGYTSKWTNYYSIVLTGAAFYHRY 645
            :|.| |.:|||.|.|.|||:||:|:||||.|.|.||...:.|.|.|:|||..|:|||||||||:|
 Frog   539 DDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMSKWKYESEWTNEVSMVLTGAAFYHKY 603

  Fly   646 YNYLYT--------NWLSLLLLKTVQQSSNCEDILMNLLVSHVTRKPPIKVTQRKGYKDRE---- 698
            :|||||        ||        |....|||||.||.||::||.|.|||||.||.:|..|
 Frog   604 FNYLYTYKMPGDIKNW--------VDAHMNCEDIAMNFLVANVTGKAPIKVTPRKKFKCPECTAI 660

  Fly   699 TGRSPWNDPDHFIQRQSCLNTFAAVFGYMPLIRSNLRMDPMLYRDPVSNLRKKYRQIELVGS 760
            .|.|  .|..|.::|..|:|.||:|||.|||.....|.||:||:|   :..:|.:....:||
 Frog   661 DGLS--LDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKD---DFPEKLKSFPNIGS 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ttv	NP_001356963.1	Exostosin	102..393	CDD:397245	96/304 (32%)
		Glyco_transf_64	477..737	CDD:430488	113/274 (41%)
ext2	NP_001120887.1	Exostosin	100..380	CDD:397245	96/306 (31%)
		Glyco_transf_64	456..697	CDD:430488	113/274 (41%)