|
Fly 89 PIPPEKKPMAPSEEAAVSTAPAPPTRLICSRRIQQQQQVKAAAAAAA--------AAAAAAAAAA 145
|..|..|.::||:: .:..|....|...::.:||||.:.:.:.:: ..||:.:..|
Human 147 PTIPAGKVISPSQK---HSKKALKQALKQQQQKKQQQQCRPSISISSNQHLSLKTVKAASDSVPA 208
Fly 146 AAAQAQATSSYPSAISPGSKAGTSQASTMREVLASIPGFSVKPRRRSNKKLTTAAQIEQTKDGKI 210
..|..:...|.....|| :...|..|:..:|..::.|...|..:||.:..| .|:::||...|
Human 209 KPATWEGKQSDGQTGSP--QNSNSSFSSSVKVENTLLGLGKKSFQRSERLHT--RQMKRTKCADI 269
Fly 211 DLETPDSILASTNLRALLNKQTFSLLPPLYQYNLIQLLPSVDREASELEQPSSSASGGSPSEAIR 275
|:|||||||.:||||||:||.|||:||...|..|:.|||.|||:. .|...::
Human 270 DVETPDSILVNTNLRALINKHTFSVLPGDCQQRLLLLLPEVDRQV-------------GPDGLMK 321
Fly 276 LSASCLNNEFFARACLEWRERLSEGEFTPENQLKLKTEAEREKNKLDPWKLKHFEPFWGEKNSRG 340
|:.|.||||||..|...|:|||||||||||.|::::.|.|:|| |::|||.:.||.::|:.:...
Human 322 LNGSALNNEFFTSAAQGWKERLSEGEFTPEMQVRIRQEIEKEK-KVEPWKEQFFESYYGQSSGLS 385
Fly 341 -KDKDKLESDCKNQKLSASIKSEPKP------------PATSQQK----------PLQQATCDNE 382
:|..||.:...:.|:..:...:||. |..||.: |.::..|:::
Human 386 LEDSKKLTASPSDPKVKKTPAEQPKSMPVSEASLIRIVPVVSQSECKEEALQMSSPGRKEECESQ 450
Fly 383 TELKFDLSTKCETTSAKTTVAVAVADKSSTFPPTGSQNNVLNEQQRRVLKRPSSSPSQ--RKQAP 445
.|::.:.||..|...:. |:...:.||..|....::..|.|| :|.:|..| .|...
Human 451 GEVQPNFSTSSEPLLSS---ALNTHELSSILPIKCPKDEDLLEQ------KPVTSAEQESEKNHL 506
Fly 446 TTIATINLDDDLDELPSTSKDSKQPKMDE--IVPNASGNV----VAAPMVDVVDHSAVEMK---- 500
||.:..|..:..:.|.::....|.|.::: :.|.|.... :..|:..:||.|...:|
Human 507 TTASNYNKSESQESLVTSPSKPKSPGVEKPIVKPTAGAGPQETNMKEPLATLVDQSPESLKRKSS 571
Fly 501 ---------------IKDEQQHQR----QHQPLINSTCDKIEPSECSKEMIVAMKQVDSKEDVDS 546
:.:.:|||: ..||.:|.. |:|: ..|....|..|..
Human 572 LTQEEAPVSWEKRPRVTENRQHQQPFQVSPQPFLNRG-DRIQ----------VRKVPPLKIPVSR 625
Fly 547 IASAAAMPAIAAVTPHTPKPEAL-APNPDVANQFVSYLQNVELAAETKAPLDNSNEADITTGTNS 610
|:.....| :.|:|....|.:: :||...|..........:|....:|
Human 626 ISPMPFHP--SQVSPRARFPVSITSPNRTGARTLADIKAKAQLVKAQRA---------------- 672
Fly 611 HDFVFSDTIDHAAYFQEHQSTINHNFFTSSSSSNTATTAANKLEEHSDKPEDSPLPIASSISGST 675
:::::..|..||: ....:|......|..
Human 673 ----------------------------AAAAAAAAAAAAS---------VGGTIPGPGPGGGQG 700
Fly 676 PASSITSTSCTSSSSSSASMSSSCSSSNSGSTTTAPTTSSSAGA----PTAPLTL-AAAAETTLA 735
|.......:....|.. |...|.:..|.|.....|.|..|. |..|.|. .:..:||.:
Human 701 PGEGGEGQTARGGSPG----SDRVSETGKGPTLELAGTGSRGGTRELLPCGPETQPQSETKTTPS 761
Fly 736 NVQAMLSTVAKLQQQQQELPVELNSNEMYQ-----HVQHDWNFGDIKLSSSQSSGDQQRNLSHEA 795
..|....:.|:|||.....|....|..... |:: ...:.||:.::::.
Human 762 QAQPHSVSGAQLQQTPPVPPTPAVSGACTSVPSPAHIE---KLDNEKLNPTRATA---------- 813
Fly 796 IDLMDVVQDADVIDDIMHNDVCHDVLGDEDEGDQEEDEDDEVVECMTEEQQLIDEDSEAVREIVD 860
.:..:.| .:|.. .|..|:..
Human 814 -----------TVASVSH-----------PQGPS---------SCRQEKAP-------------- 833
Fly 861 KLQQHQQQQNQQQHHQQLHIQDVVQLAQHSFMPQAHSEFGNDIGQEMLCDAVPMSAA-----EME 920
:..|..::..|.|:..| |::
Human 834 ----------------------------------------SPTGPALISGASPVHCAADGTVELK 858
Fly 921 VS-STVITNSSNSNDSSNNI-------SLCSSTNSLTINQMP---HQASQQPQQNAQSNAQQQRQ 974
.. |..|.|.|.|:.:..:: .|.|...:.|:.::| ..|:..|..:|..::
Human 859 AGPSKNIPNPSASSKTDASVPVAVTPSPLTSLLTTATLEKLPVPQVSATTAPAGSAPPSS----- 918
Fly 975 ILVDSNGQIIGNFLLQQQRQQQQQQLLQQFTLQAAAAQQQQQQQQQHQQQQQQQQQATSSNSLGK 1039
||.||:: .:...||.|..|.
Human 919 ------------------------------TLPAASS---------------LKTPGTSLNMNGP 938
Fly 1040 TLPVALRNGTQQFLSPNLIAQQHQQQQQQQLEQHQQQATAQQKHQQIQQFALQQAQLHQRQLLAQ 1104
|| |...:.
Human 939 TL---------------------------------------------------------RPTSSI 946
Fly 1105 AANNNLLQQQQQQQQNVALPTTQAKFIAKPLNIISM-TRPANASP-------TTAATTANTASIP 1161
.|||.|:.|..|.:. :|..| .:.|||..:.| |.|..|.. ....||.|:
Human 947 PANNPLVTQLLQGKD---VPMEQ--ILPKPLTKVEMKTVPLTAKEERGMGALIATNTTENS---- 1002
Fly 1162 SAYANVVAVTGAQQQQSPPVPAPQQQ---TVQQQQLANHNSNMQQLPNVLTM---KTLPPSGVPT 1220
|..:..:....||.||| |:|.:|| .|:|..|.: |.|..|.:.|
Human 1003 ---------TREEVNERQSHPATQQQLGKTLQSKQL-------PQVPRPLQLFSAKELRDSSIDT 1051
Fly 1221 TIAQQRLQPKMPTGKGRKATSNRLPPGAVNLERSYQICQAVIQNSPNRENLKAQLRPPAAILNQH 1285
....:.|. |||.: ||.|.:||. ..|:||.:.: ||:.....|
Human 1052 HQYHEGLS---------KATQD-------------QILQTLIQR-VRRQNLLSVV-PPSQFNFAH 1092
Fly 1286 Q------------------PTTTTAPAPINPVTLNVSTVA--------------------ATP-- 1310
. ...|:.||......||:||.. ::|
Human 1093 SGFQLEDISTSQRFMLGFAGRRTSKPAMAGHYLLNISTYGRGSESFRRTHSVNPEDRFCLSSPTE 1157
Fly 1311 -----MSNITTATGSMAAA--------VAAAPPQNVLKQEELLVSGAVGAGALPAGLPPNVMGVG 1362
.::...|||..::: ......::|..:||..||.:.|.|...:|
Human 1158 ALKMGYTDCKNATGESSSSKEDDTDEESTGDEQESVTVKEEPQVSQSAGKGDTSSG--------- 1213
Fly 1363 RPGVYKVIGPRMSGFPRKKYVQRKPSPTTLIRHVFSPGPGGATATAQQLQMLQQHHQSTTSPVPV 1427
|..:.. ...|.....::|.:..|.....|..:...|....|:.......
Human 1214 ---------------PHSRET-LSTSDCLASKNVKAEIPLNEQTTLSKENYLFTRGQTFDEKTLA 1262
Fly 1428 QNPQQPAPEQLIHQNGNGQYVLVHRANVGAADNQAPR--ASSAPPMHQNQFVTVQNPLHSINGIP 1490
::..|.|.:|:.| |..|.|...:|. :|:..|: ...:|.|
Human 1263 RDLIQAAQKQMAH------------AVRGKAIRSSPELFSSTVLPL------PADSPTH------ 1303
Fly 1491 MGGRGRPASVDTTAGSGNVIAPPISATDALHHHHHEMQQQQQHQQPQPLG-------NVGAAANI 1548
:| ::.|| :|..:.:..|..:| ||..::::
Human 1304 -----QP-----------LLLPP-------------LQTPKLYGSPTQIGPSYRGMINVSTSSDM 1339
Fly 1549 VRRNIAAGPNIAYIDGSNTNSSAVALMEAGNNYIVTTNASPTAAPSPINQQPQSQPTGTQHQHPL 1613
...:...|..:: ||... :::.:.:.|..|:.....|.|.
Human 1340 DHNSAVPGSQVS----SNVGD------------VMSFSVTVTTIPASQAMNPSSH---------- 1378
Fly 1614 LQLHQTGENTP-----PGNEATATANNCACSLNAMVICQQCGAFCHDDCIGAAKLCVACVI 1669
|:..| ..|....|.:.|.|.|.||::|:.|||||||||||.:||||:|::
Human 1379 ------GQTIPVQAFSEENSIEGTPSKCYCRLKAMIMCKGCGAFCHDDCIGPSKLCVSCLV 1433
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