DRSC/TRiP Functional Genomics Resources

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Protein Alignment Oaz and IKZF5

DIOPT Version :9

Sequence 1:NP_001188929.1 Gene:Oaz / 36609 FlyBaseID:FBgn0284250 Length:1366 Species:Drosophila melanogaster
Sequence 2:NP_001258769.1 Gene:IKZF5 / 64376 HGNCID:14283 Length:419 Species:Homo sapiens


Alignment Length:498 Identity:108/498 - (21%)
Similarity:166/498 - (33%) Gaps:131/498 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   220 GEDLPKP-KRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKMGATAGGGATGAASKFDKLTGEG 283
            ||..|:| ..:..|..:.....||...:.     ..::.:.:..|..|.|..|..:..|..:.|.
Human     2 GEKKPEPLDFVKDFQEYLTQQTHHVNMIS-----GSVSGDKEAEALQGAGTDGDQNGLDHPSVEV 61

  Fly   284 IKSRGDGSYQCQFCEKTFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNY 348
            ......|.....| |:||.  |.|             ||.||:...|.......|.::||.|:.:
Human    62 SLDENSGMLVDGF-ERTFD--GKL-------------KCRYCNYASKGTARLIEHIRIHTGEKPH 110

  Fly   349 KCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNA 413
            :|..|..|.:...||:.||::|..:||::|.:|:...:..:.|:.|.::..|...|         
Human   111 RCHLCPFASAYERHLEAHMRSHTGEKPYKCELCSFRCSDRSNLSHHRRRKHKMVPI--------- 166

  Fly   414 LNYSPRSTGSASASVSSNGSLQKRRYAL-----ALASDSSPSRM--------DF----PKRSRSN 461
                 :.|.|:.:|....|.|||:...|     ||.:.|.||.:        ||    |.....:
Human   167 -----KGTRSSLSSKKMWGVLQKKTSNLGYSRRALINLSPPSMVVQKPDYLNDFTHEIPNIQTDS 226

  Fly   462 HVGGTTTTAT------------PTPLLRCSYCPKVTEFSSLEQLNAHLQS------------VHE 502
            :.....||.|            ..||.:.|  ....:.|||...|.:..|            :.:
Human   227 YESMAKTTPTGGLPRDPQELMVDNPLNQLS--TLAGQLSSLPPENQNPASPDVVPCPDEKPFMIQ 289

  Fly   503 QPQTQAVKTPVQEGEGFQLSCEYCTMKFGNIAGLFQHMRSTHMDRLSSPNSYYEHFNRLATAGTF 567
            ||.||||.:.|                            |..:.:.|||.|.             
Human   290 QPSTQAVVSAV----------------------------SASIPQSSSPTSP------------- 313

  Fly   568 SPRLALDLPKIKPDLGSPERESRPAEDDLPTDLSNNKRRPLTPNPQAQTPLAPPSAPPGVFFCNQ 632
            .||.:.......|..|.   .|.|:.......:.|:  :|.||     .|..|...|..:..|..
Human   314 EPRPSHSQRNYSPVAGP---SSEPSAHTSTPSIGNS--QPSTP-----APALPVQDPQLLHHCQH 368

  Fly   633 CNAGLPDFESFRNHLKSHIAEGMQLVCPHCGMSLPEQSEFERH 675
            |:....|...:..|:..|..|. ...|..||.....:.:|..|
Human   369 CDMYFADNILYTIHMGCHGYEN-PFQCNICGCKCKNKYDFACH 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
OazNP_001188929.1 C2H2 Zn finger 294..314 CDD:275368 6/19 (32%)
C2H2 Zn finger 322..342 CDD:275368 5/19 (26%)
zf-H2C2_2 334..359 CDD:290200 7/24 (29%)
COG5048 336..769 CDD:227381 83/381 (22%)
zf-C2H2 348..370 CDD:278523 7/21 (33%)
C2H2 Zn finger 350..370 CDD:275368 7/19 (37%)
C2H2 Zn finger 378..398 CDD:275368 4/19 (21%)
C2H2 Zn finger 630..650 CDD:275368 4/19 (21%)
C2H2 Zn finger 659..679 CDD:275368 5/17 (29%)
C2H2 Zn finger 689..707 CDD:275368
C2H2 Zn finger 1020..1041 CDD:275368
C2H2 Zn finger 1049..1069 CDD:275368
C2H2 Zn finger 1197..1217 CDD:275368
C2H2 Zn finger 1229..1246 CDD:275368
C2H2 Zn finger 1258..1278 CDD:275368
IKZF5NP_001258769.1 C2H2 Zn finger 84..104 CDD:275368 5/19 (26%)
zf-H2C2_2 96..121 CDD:404364 7/24 (29%)
C2H2 Zn finger 112..132 CDD:275368 7/19 (37%)
zf-H2C2_2 124..148 CDD:404364 9/23 (39%)
C2H2 Zn finger 140..158 CDD:275368 4/17 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 223..247 3/23 (13%)
PHA03269 251..>361 CDD:165527 32/162 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 262..356 28/144 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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