DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Oaz and CG2120

DIOPT Version :9

Sequence 1:	NP_001188929.1	Gene:	Oaz / 36609	FlyBaseID:	FBgn0284250	Length:	1366	Species:	Drosophila melanogaster
Sequence 2:	NP_572446.2	Gene:	CG2120 / 31737	FlyBaseID:	FBgn0030005	Length:	315	Species:	Drosophila melanogaster

Alignment Length:	256	Identity:	69/256 - (26%)
Similarity:	96/256 - (37%)	Gaps:	50/256 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1041 HNSTGK-HKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGAS 1104
            |.:||| |.|.|||..|.....|..||:.|:. .:...|..||:....:...|.|...|   .|.
  Fly    92 HRTTGKDHTCDICDRRFSEAYNLRIHKMTHTD-EKPHVCVECGKGFRQLNKLRIHAVTH---TAE 152

  Fly  1105 LPLACICCRQTLHSEFELSLHAKFHTKSSSSGGSLQEPVCALCLEPLPDATEGPAKLCDKCCRK- 1168
            .|..|..|.:.......|::|.:.||      |....|    ||     ||:         |..
  Fly   153 RPHKCDICGKGFRYANYLTVHRRLHT------GEKPYP----CL-----ATD---------CHLS 193

  Fly  1169 -HNLNGKR----GKHSEPATSLPAPPSAFVENR--------CNLCKMILPHAQKLQEHLVEHTFA 1220
             |:::.:|    .:|:......|..|.|..|.|        |.:|..:|.....|..||..|
  Fly   194 FHSIHARRIHTKLRHAAQTDPDPEHPLAEQEQRDTSALSFTCPVCSRVLTDQCYLSIHLKRH--- 255

  Fly  1221 GTEQRGFNC--YICSAVFTAPGGLLNHMGEHGAHSRPYDCNLCPEKFFFRAELEHHQRGHE 1279
             ..||.|.|  ..|...|.:...|.:|...| ...||:.|.|||.:|..::..:.|.:.||
  Fly   256 -YNQRDFPCPQPECGKRFFSASELKHHQIAH-TQQRPFACPLCPARFLRKSNHKQHLKVHE 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Oaz	NP_001188929.1	C2H2 Zn finger	294..314	CDD:275368
		C2H2 Zn finger	322..342	CDD:275368
		zf-H2C2_2	334..359	CDD:290200
		COG5048	336..769	CDD:227381
		zf-C2H2	348..370	CDD:278523
		C2H2 Zn finger	350..370	CDD:275368
		C2H2 Zn finger	378..398	CDD:275368
		C2H2 Zn finger	630..650	CDD:275368
		C2H2 Zn finger	659..679	CDD:275368
		C2H2 Zn finger	689..707	CDD:275368
		C2H2 Zn finger	1020..1041	CDD:275368	69/256 (27%)
		C2H2 Zn finger	1049..1069	CDD:275368	8/19 (42%)
		C2H2 Zn finger	1197..1217	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1229..1246	CDD:275368	4/18 (22%)
		C2H2 Zn finger	1258..1278	CDD:275368	6/19 (32%)
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	8/19 (42%)
		zf-H2C2_2	113..138	CDD:290200	7/25 (28%)
		C2H2 Zn finger	129..149	CDD:275368	5/19 (26%)
		zf-H2C2_2	142..166	CDD:290200	7/26 (27%)
		COG5048	151..>264	CDD:227381	33/140 (24%)
		C2H2 Zn finger	157..177	CDD:275368	4/19 (21%)
		C2H2 Zn finger	185..206	CDD:275368	7/34 (21%)
		C2H2 Zn finger	235..255	CDD:275368	6/19 (32%)
		C2H2 Zn finger	263..285	CDD:275368	5/21 (24%)
		C2H2 Zn finger	293..313	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446547
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930