DRSC/TRiP Functional Genomics Resources

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Protein Alignment Oaz and IKZF2

DIOPT Version :9

Sequence 1:NP_001188929.1 Gene:Oaz / 36609 FlyBaseID:FBgn0284250 Length:1366 Species:Drosophila melanogaster
Sequence 2:XP_011509104.1 Gene:IKZF2 / 22807 HGNCID:13177 Length:533 Species:Homo sapiens


Alignment Length:649 Identity:140/649 - (21%)
Similarity:217/649 - (33%) Gaps:217/649 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   122 HCKSSGHEEDAVDAEEPEDLELDDELLSLSGDEDYDDEELQSLDSFYSDMYSTHTSSSYSPSISD 186
            ||..: .|.:|:|.            ...|||.:...|.      .:|:|....|||        
Human     2 HCTLT-METEAIDG------------YITSGDNELSPER------EHSNMAIDLTSS-------- 39

  Fly   187 GTMTPNSHHLIGAPTAAGQEDHPT----------------------EGKINGGADGEDLPKPKRL 229
               |||..|  .:|:      |.|                      |.:|.|..:|..|.:|.  
Human    40 ---TPNGQH--ASPS------HMTSTNSVKLEMQSDEECDRKPLSREDEIRGHDEGSSLEEPL-- 91

  Fly   230 PHFHHHHHHHYHHQQALKIANKLRKINKEAKMGATAGGGATGAASKFDKLTGEGIKSRGDGSYQC 294
                         .::.::|:. ||:                     .:|.|||.....:|..:|
Human    92 -------------IESSEVADN-RKV---------------------QELQGEGGIRLPNGKLKC 121

  Fly   295 QFCEKTFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSR 359
            ..|.........|..|.:||....||.|..|...|..|.:..||.|||:.|:.:|||.|..|..|
Human   122 DVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCSYACRR 186

  Fly   360 SDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQK---HKKNAAILAAGGNPNALNYSPRST 421
            .|.|..|::||.:.||.:|:.|.|.|...::|..|.::   :.:|.::.|| |...:.:..|...
Human   187 RDALTGHLRTHSVGKPHKCNYCGRSYKQRSSLEEHKERCHNYLQNVSMEAA-GQVMSHHVPPMED 250

  Fly   422 GSASASVSSN-----------------GSLQKRRYALALASDSSPSRMDFPKRSRSNHVGGTTTT 469
            ......:..|                 |::.||:       .|:|.:.          ||     
Human   251 CKEQEPIMDNNISLVPFERPAVIEKLTGNMGKRK-------SSTPQKF----------VG----- 293

  Fly   470 ATPTPLLRCSYCPKV------TEFSSLEQLNAHLQSVHEQPQTQAVKTPVQEGEGFQLSCEYCTM 528
               ..|:|.|| |.:      |.....|.:.:|:..       ||:...:.     .|..|    
Human   294 ---EKLMRFSY-PDIHFDMNLTYEKEAELMQSHMMD-------QAINNAIT-----YLGAE---- 338

  Fly   529 KFGNIAGLFQHMRSTHMD---RLSSPNSYYEHFNRL------ATAGTFSPRLALDLPKIKPDLGS 584
               .:..|.||..||..:   .:||..|...|.||:      .||.:....:...:..|:|....
Human   339 ---ALHPLMQHPPSTIAEVAPVISSAYSQVYHPNRIERPISRETADSHENNMDGPISLIRPKSRP 400

  Fly   585 PERESRPAE---DDLPTDLSNNKRRPLTPNP-----QAQTP---------LAPPSAPPG------ 626
            .|||:.|:.   |...::.|::..:....:|     :.|:|         |....||.|      
Human   401 QEREASPSNSCLDSTDSESSHDDHQSYQGHPALNPKRKQSPAYMKEDVKALDTTKAPKGSLKDIY 465

  Fly   627 -----------VFFCNQCNAGLPDFESFRNHLKSHIAEGMQ--LVCPHCGMSLPEQSEFERHVV 677
                       .|.|..|.....|...:..|:..|   |.:  |.|..||....::.||..|:|
Human   466 KVFNGEGEQIRAFKCEHCRVLFLDHVMYTIHMGCH---GYRDPLECNICGYRSQDRYEFSSHIV 526

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
OazNP_001188929.1 C2H2 Zn finger 294..314 CDD:275368 4/19 (21%)
C2H2 Zn finger 322..342 CDD:275368 7/19 (37%)
zf-H2C2_2 334..359 CDD:290200 11/24 (46%)
COG5048 336..769 CDD:227381 93/413 (23%)
zf-C2H2 348..370 CDD:278523 9/21 (43%)
C2H2 Zn finger 350..370 CDD:275368 8/19 (42%)
C2H2 Zn finger 378..398 CDD:275368 6/22 (27%)
C2H2 Zn finger 630..650 CDD:275368 4/19 (21%)
C2H2 Zn finger 659..679 CDD:275368 7/19 (37%)
C2H2 Zn finger 689..707 CDD:275368
C2H2 Zn finger 1020..1041 CDD:275368
C2H2 Zn finger 1049..1069 CDD:275368
C2H2 Zn finger 1197..1217 CDD:275368
C2H2 Zn finger 1229..1246 CDD:275368
C2H2 Zn finger 1258..1278 CDD:275368
IKZF2XP_011509104.1 C2H2 Zn finger 121..141 CDD:275368 4/19 (21%)
zf-H2C2_2 134..158 CDD:290200 9/23 (39%)
COG5048 145..>214 CDD:227381 29/68 (43%)
C2H2 Zn finger 149..169 CDD:275368 7/19 (37%)
zf-H2C2_2 161..186 CDD:290200 11/24 (46%)
C2H2 Zn finger 177..197 CDD:275368 8/19 (42%)
C2H2 Zn finger 205..226 CDD:275368 6/20 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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