DRSC/TRiP Functional Genomics Resources

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Protein Alignment Oaz and IKZF3

DIOPT Version :9

Sequence 1:NP_001188929.1 Gene:Oaz / 36609 FlyBaseID:FBgn0284250 Length:1366 Species:Drosophila melanogaster
Sequence 2:NP_036613.2 Gene:IKZF3 / 22806 HGNCID:13178 Length:509 Species:Homo sapiens


Alignment Length:632 Identity:123/632 - (19%)
Similarity:208/632 - (32%) Gaps:198/632 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   102 ELQHPRDEVVASDAAANANGHCKSSGHEEDAVDAEEPEDLELDDELLSLSGDEDYDDEELQSLDS 166
            ||:..:::.|.:::||..|.:..:..||.:.||:.|....|          |||..|:.::..|.
Human     9 ELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANE----------DEDIGDDSMKVKDE 63

  Fly   167 FYSDMYSTHTSSSYSPSISDGTMTPNSHHLIGAPTAAGQEDHPTEGKINGGADGEDLPKPKRLPH 231
             ||:                                  ::::..:.:..|.|:..::|       
Human    64 -YSE----------------------------------RDENVLKSEPMGNAEEPEIP------- 86

  Fly   232 FHHHHHHHYHHQQALKIANKLRKINKEAKMGATAGGGATGAASKFDKLTGEGIKSR-GDGSYQCQ 295
              :.:...|:..:.:|:...:                     ..||       .|| ..|...|.
Human    87 --YSYSREYNEYENIKLERHV---------------------VSFD-------SSRPTSGKMNCD 121

  Fly   296 FCEKTFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRS 360
            .|..:......|..|.:||....||:|..|...|..|.:..||.||||.|:.:||..|..|..|.
Human   122 VCGLSCISFNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHTGEKPFKCHLCNYACQRR 186

  Fly   361 DHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSA- 424
            |.|..|::||.::||::|..|.|.|...::|    ::||:.........:|.       .|.|| 
Human   187 DALTGHLRTHSVEKPYKCEFCGRSYKQRSSL----EEHKERCRTFLQSTDPG-------DTASAE 240

  Fly   425 ----SASVSSNGSLQKRRYA--LALASDSSPSRMDFPKRS------RSNHVGGTTTTATPTPLLR 477
                .|.:.|..:|...|.|  :|....|.|.:....||.      .|:::....:....|.::.
Human   241 ARHIKAEMGSERALVLDRLASNVAKRKSSMPQKFIGEKRHCFDVNYNSSYMYEKESELIQTRMMD 305

  Fly   478 CSYCPKVTEFSSLEQLNAHLQSVHEQPQTQAVKTPVQE-----GEGFQLSCEYCTMKFGNIAGLF 537
                      .::....::|.:...:|..|....|..|     ...:.::.....|..|....| 
Human   306 ----------QAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQEL- 359

  Fly   538 QHMRSTHMDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLGSPERESRP---AEDDLPTD 599
             ..:|.|:...|.|:                                 ||...|   ..|...||
Human   360 -EKKSIHLPEKSVPS---------------------------------ERGLSPNNSGHDSTDTD 390

  Fly   600 LSNNKRR------------------PLTPN-PQAQTPLAPPSAPP--------------GVFFCN 631
            .::.:|:                  ||... |::...|.||...|              .|:.|:
Human   391 SNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCD 455

  Fly   632 QCNAGLPDFESFRNHLKSHIAEGMQ--LVCPHCGMSLPEQSEFERHV 676
            .|.....|:..|..|:..|   |.:  ..|..||....::.||..|:
Human   456 HCRVLFLDYVMFTIHMGCH---GFRDPFECNMCGYRSHDRYEFSSHI 499

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
OazNP_001188929.1 C2H2 Zn finger 294..314 CDD:275368 4/19 (21%)
C2H2 Zn finger 322..342 CDD:275368 7/19 (37%)
zf-H2C2_2 334..359 CDD:290200 11/24 (46%)
COG5048 336..769 CDD:227381 82/397 (21%)
zf-C2H2 348..370 CDD:278523 8/21 (38%)
C2H2 Zn finger 350..370 CDD:275368 7/19 (37%)
C2H2 Zn finger 378..398 CDD:275368 5/19 (26%)
C2H2 Zn finger 630..650 CDD:275368 5/19 (26%)
C2H2 Zn finger 659..679 CDD:275368 6/18 (33%)
C2H2 Zn finger 689..707 CDD:275368
C2H2 Zn finger 1020..1041 CDD:275368
C2H2 Zn finger 1049..1069 CDD:275368
C2H2 Zn finger 1197..1217 CDD:275368
C2H2 Zn finger 1229..1246 CDD:275368
C2H2 Zn finger 1258..1278 CDD:275368
IKZF3NP_036613.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..86 21/121 (17%)
COG5048 <79..>219 CDD:227381 45/180 (25%)
C2H2 Zn finger 120..140 CDD:275368 4/19 (21%)
zf-H2C2_2 133..157 CDD:316026 9/23 (39%)
C2H2 Zn finger 148..168 CDD:275368 7/19 (37%)
C2H2 Zn finger 176..196 CDD:275368 7/19 (37%)
C2H2 Zn finger 204..220 CDD:275368 5/19 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 364..394 9/62 (15%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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