DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Achl and larp6-like.1

DIOPT Version :9

Sequence 1:	NP_001286419.1	Gene:	Achl / 36605	FlyBaseID:	FBgn0033936	Length:	867	Species:	Drosophila melanogaster
Sequence 2:	NP_001072636.1	Gene:	larp6-like.1 / 780092	XenbaseID:	XB-GENE-5806148	Length:	481	Species:	Xenopus tropicalis

Alignment Length:	472	Identity:	128/472 - (27%)
Similarity:	201/472 - (42%)	Gaps:	116/472 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 NSPVLEAKRTHRSFLTMKKEKEVEPPQEKEQEVPVHQEQDTEPQG---------------PNEID 269
            :||...::|:..|                .:.:||..:|.:...|               .:.:|
Frog     2 SSPCCSSQRSPSS----------------SRSIPVGVQQHSFDSGLVLRERNNSSCHHSQNDHLD 50

  Fly   270 TLDPSL-----------------IPSEELAAEITDAVEFYFSNESILKDAFLLKHVRRNKEGFVS 317
            :||.|.                 ||..:|..:|...||||.|:|::..||||||||::||.|:||
Frog    51 SLDGSFFDFTETLDDSSYEGDSGIPDLKLVRKIVSQVEFYLSDENLSHDAFLLKHVQKNKMGYVS 115

  Fly   318 LKLVSSFKRVRQLTREWKVVGDAVRRKSRKIELNDVGTKVRRIEPLPSF-------------DET 369
            :||::|||:::.|||:|:....|: |.|.::|:|:..|||||..|||.:             :.:
Frog   116 IKLLTSFKKIKYLTRDWRKTLYAL-RFSEQLEVNEEETKVRRKNPLPDYLLGLPPTKQLLVWNIS 179

  Fly   370 MPSRTIVACDLPLDKLTIEKVSDLFSPCGEIALIRILKPGMAIPVDVRQFMNKYPELQQKECALV 434
            .|.:...:|.   .|..:|.|:.:|:..|.|..|||||||..:|.|:|::|::||||..:.||||
Frog   180 DPEKRSFSCQ---QKNLMEIVTSVFATYGLITSIRILKPGKEVPSDIRKYMSRYPELSTRNCALV 241

  Fly   435 EYLESSSARDA-RHLNGPFQVYEM----VAPKKKTG-KKAAVIQIA------APVARMV-ENYRY 486
            ||.....||.| ..|:|......:    |.|....| :|..||..|      .|..:|. :..|.
Frog   242 EYESLEGARKALEALSGKVSSTNIDRIKVIPVSGRGTRKKNVIDTAEQEDLDLPDKKMTRKEIRA 306

  Fly   487 YNDANYERSRGGSFSGHETVPDLRFKLKRNNSDFQPS----YYQQTGPSYHANPYQHYQPRGSIG 547
            .....|.......:|..|             ||..|:    ..:...|...::|...::|
Frog   307 MERLQYTTEDSSFYSSSE-------------SDSTPASPVLAPRYLSPLTFSSPSMMFKP----- 353

  Fly   548 NQNQEVGPNGFFGYGPRRYSNTSTISANTAAALG--DVSPISSAVNSGGNPMVSGISSLQRRLSN 610
                     .||. .||    .||:.|..:.:..  :.||::|.:..|..|.........|::.:
Frog   354 ---------PFFS-SPR----PSTLYARKSLSFSPHNPSPLASELGIGDYPSPGTSPEFSRKILD 404

  Fly   611 CSEQNYTPEVNPSMSRR 627
            .|.:|.....:|.:.||
Frog   405 HSAENAMSSTSPWVQRR 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Achl	NP_001286419.1	LARP_6	282..359	CDD:153402	37/76 (49%)
Achl	NP_001286419.1	RRM_LARP6	373..472	CDD:240735	38/104 (37%)
larp6-like.1	NP_001072636.1	LARP_6	80..156	CDD:153402	37/76 (49%)
larp6-like.1	NP_001072636.1	RRM_LARP6	171..274	CDD:240735	36/105 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I8813
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005698
OrthoInspector	1	1.000	-	-		otm47663
Panther	1	1.100	-	-	O	PTHR22792
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3569
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.010