DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Achl and SPAC1527.03

DIOPT Version :9

Sequence 1:	NP_001286419.1	Gene:	Achl / 36605	FlyBaseID:	FBgn0033936	Length:	867	Species:	Drosophila melanogaster
Sequence 2:	NP_594554.1	Gene:	SPAC1527.03 / 2541645	PomBaseID:	SPAC1527.03	Length:	475	Species:	Schizosaccharomyces pombe

Alignment Length:	345	Identity:	73/345 - (21%)
Similarity:	131/345 - (37%)	Gaps:	75/345 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 SPASMDKTKEMEEL-DDEQPSCSSQA--------------VVPLSSSLPCKLLRMHARRSAQALL 101
            ||...:|..|..:| ||.|...:.:|              ..|:|:....:.....:||:...
pombe   116 SPEIAEKQVEDRKLSDDSQKPLAPKANGKEKWVTITPNFTHTPISNRKSSRSRNDGSRRNGNG-- 178

  Fly   102 HQMESMDSQLG--SSNGSTSEDTSPSAPPMSPTDHQLVDVGMGSSIGDSDESSEEGDELKPLAVD 164
                   .:.|  ||:||....|:.|.           :.....||..|:.|:|..|::
pombe   179 -------RRRGNYSSHGSNKRQTNYSR-----------EKDASRSIDSSNPSAEYRDDI------ 219

  Fly   165 NHIIAEVDLTERQTTPPAVLSEANLEKFRKHQMDNIYLHPNFTLDASPPPAVAPANSPVLEAKRT 229
                       ..|.....:|.||.::..:...|:....|:.:..:...|:....|....:...:
pombe   220 -----------NNTFGSQTVSSANGKEVPQTSEDSSSQAPHHSSSSGHAPSQQGGNKHSYKKSDS 273

  Fly   230 HRSFLTMKKEKEVEPPQEKEQEVPVHQEQDTEPQGPN-----EIDTLDPSLIPSEELAAEITDAV 289
            .:||  ..|.:.....|........:...:.:...||     ..:.::|.|.   ::.|.:|..:
pombe   274 QQSF--HHKGRNTRKGQRHNNGFYRNIANNIQGPFPNYPVVVNGNGVNPYLC---DVQAFLTSQL 333

  Fly   290 EFYFSNESILKDAFLLKHVRRNKEGFVSLKLVSSFKRVRQLTREWKVVGDAVRRK---SRKIEL- 350
            |:|||.|::.||.||.||:  :.||:|.|..::||.|::..:.:..::..|.:..   ...|:|
pombe   334 EYYFSIENLCKDMFLRKHM--DDEGYVPLAFLASFNRIKSFSTDLNLLHAACKASDIIDVAIDLQ 396

  Fly   351 NDVGTKVRRIEP-----LPS 365
            :.:..||||.|.     |||
pombe   397 SPMSIKVRRKETWSPWILPS 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Achl	NP_001286419.1	LARP_6	282..359	CDD:153402	25/80 (31%)
Achl	NP_001286419.1	RRM_LARP6	373..472	CDD:240735
SPAC1527.03	NP_594554.1	LHP1	4..473	CDD:227520	73/345 (21%)
SPAC1527.03	NP_594554.1	LA	323..406	CDD:128955	26/87 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900